Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-007021 |
CAS: 60504-72-5 |
Molecular Formula: C6H11DO6 |
Molecular Weight: 181.17 |
Chemical Structure |
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Description | Isotope labelled D-Fructose, a monosaccharide that naturally occurs in numerous fruits and plants. |
Synonyms | Advantose FS 95-4-d; D-(-)-Fructose-4-d; D-(-)-Levulose-4-d; D-Arabino-2-hexulose-4-d; Fructose-4-d; Fruit Sugar-4-d; Fujifructo L 95-4-d; Furucton-4-d; Hi-Fructo 970-4-d; Krystar-4-d; Krystar 300-4-d; Levulose-4-d; Nevulose-4-d; Sugar Fruit-4-d; D-Fructose-4-d1; D-Fructose-4-C-d |
IUPAC Name | (3S,4R,5R)-4-deuterio-1,3,4,5,6-pentahydroxyhexan-2-one |
Related CAS | 57-48-7 (unlabelled) |
Solubility | Soluble in Methanol, Water |
Appearance | White to Off-white Solid |
Storage | Store at -20°C |
D-fructose-[4-d], a deuterated variant of fructose, finds diverse applications in scientific and industrial sectors. Here are the key applications of D-fructose-[4-d]:
Metabolic Tracing: Pioneering metabolic studies, D-fructose-[4-d] is a cornerstone for tracing the intricate pathways and conversions of fructose within biological systems. By substituting conventional fructose with its deuterated counterpart, researchers can meticulously monitor its integration into metabolic products through cutting-edge techniques like mass spectrometry or NMR. This methodology unveils the dynamic landscape of fructose metabolism and its profound influence on cellular physiology.
Pharmaceutical Research: In the realm of pharmaceuticals, D-fructose-[4-d] takes center stage in unraveling the complex pharmacokinetics and dynamics of drug formulations containing fructose as a crucial excipient. The labeled isotopes of D-fructose-[4-d] enable precise detection and quantification in biological samples, shedding light on intricate processes like drug absorption, distribution, metabolism, and excretion. This scientific tool unravels critical insights into drug behavior within the body, enhancing our comprehension of therapeutic interventions.
Nutrition Research: A stalwart in nutrition research, D-fructose-[4-d] plays a pivotal role in deciphering the enigmatic world of fructose absorption and its implications for dietary well-being. Researchers leverage this specialized form of fructose to explore how the body processes and utilizes fructose from diverse food sources, offering invaluable insights into dietary health and metabolic disorders such as obesity and diabetes. This investigative approach is instrumental in shaping dietary recommendations and advancing our understanding of metabolic intricacies.
Biotechnology: At the forefront of biotechnological advancements, D-fructose-[4-d] emerges as a potent tool for unraveling the intricate production pathways of biochemicals and biofuels. By infusing deuterated fructose into microbial cultures or enzymatic reactions, scientists can meticulously trace carbon flow and optimize production processes, catalyzing the engineering of metabolic pathways for heightened yield and efficiency in industrial bioprocesses. This innovative utilization of D-fructose-[4-d] redefines the landscape of biotechnological innovation, driving progress towards sustainable bio-based solutions.
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