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D-glucitol-[4-d]

General Information
Catalog: BLP-007022
Molecular Formula: C6H13DO6
Molecular Weight: 183.18
Chemical Structure
D-glucitol-[4-d]
Synonyms D-[4-D]glucitol; D-[4-2H]sorbitol; D-glucitol-4-d
IUPAC Name (2R,3R,4R,5S)-hexane-3-d-1,2,3,4,5,6-hexaol
Related CAS 50-70-4 (unlabelled)
Solubility Soluble in DMSO, Methanol
Appearance White to Off-white Solid
Storage Store at -20°C

D-glucitol-[4-d], a deuterium-labeled variant of sorbitol, a commonly employed sugar alcohol in diverse scientific and industrial realms. Here are the key applications of D-glucitol-[4-d]:

Metabolic Studies: Embedded within metabolic investigations, D-glucitol-[4-d] acts as a tracer illuminating metabolic pathways concerning sugar alcohols. By infusing this labeled compound into metabolic inquiries, scientists can meticulously outline its deployment and conversion within biological frameworks. This methodology aids in unraveling metabolic flux and unraveling the multifaceted role of sorbitol in both health and disease scenarios.

NMR Spectroscopy: A pivotal asset in nuclear magnetic resonance (NMR) spectroscopic undertakings, D-glucitol-[4-d] proffers unique deuterium-laden spectral attributes that facilitate structural delineation and dynamic assessments of carbohydrates. Researchers leverage D-glucitol-[4-d] to probe the conformational intricacies and interactions of sugar alcohols across diverse environmental contexts, paving the way for nuanced insights into molecular behaviors.

Pharmaceutical Research: Within pharmaceutical spheres, the utility of D-glucitol-[4-d] transcends as a tool for scrutinizing drug pharmacokinetics and bioavailability. As a deuterium-labeled entity, it functions as a discerning tracer for monitoring drug metabolism and distribution dynamics. This comprehension proves pivotal in refining drug formulations and enhancing therapeutic effectiveness in clinical applications.

Biomedical Research: In the realm of biomedical inquiry, D-glucitol-[4-d] serves as a conduit for delving into the impact of sorbitol on cellular processes and afflictions like diabetic complications. By harnessing the labeled variant, researchers can disentangle the specific contributions of sorbitol to pathological conditions, laying the groundwork for therapeutic strategies centered around sorbitol-influenced pathways.

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