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D-mannose-[4-d]

General Information
Catalog: BLP-007023
Molecular Formula: C6H11D2O6
Molecular Weight: 181.16
Chemical Structure
D-mannose-[4-d]
Description D-Mannose-[4-d] is a labeled analog of D-Mannose. D-mannose is important in the glycosylation of molecules. It is involved in N and O glycosylation of bovine. It is also used for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A.
Synonyms D-[4-2H]mannose; D-mannose-4-d
IUPAC Name (3S,4S,5R,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-5-d-2,3,4,5-tetraol
Related CAS 3458-28-4 (unlabelled)
Solubility Soluble in Methanol, Water
Appearance White to Off-white Solid
Storage Store at -20°C

D-mannose-[4-d], a sugar molecule with unique properties, finds widespread use in both clinical and research environments. Here are the key applications of D-mannose-[4-d]:

Urinary Tract Infections (UTIs): Renowned for its efficacy in combating UTIs, particularly those instigated by E. coli bacteria, D-mannose-[4-d] plays a crucial role in both preventing and treating these infections. By binding to E. coli microbes, it effectively hinders their adherence to the urinary tract walls, facilitating their swift expulsion from the body through urination. This mechanism significantly diminishes the risk of infection, offering a potent shield against UTIs.

Dietary Supplements: Embraced in the realm of dietary supplements for fostering urinary tract health, D-mannose-[4-d] stands as a natural antidote for those seeking an alternative to antibiotics. Touted for its efficacy in maintaining urinary tract wellness, it is a favored choice for those grappling with recurring UTIs, promising prevention without the unwanted side effects often associated with antibiotic regimens. Its popularity stems from its ability to support urinary health comprehensively.

Glycosylation Studies: A cornerstone of biochemical research, D-mannose-[4-d] assumes a pivotal role in unraveling the intricacies of glycosylation processes, vital for protein folding and function. Through its incorporation into glycoproteins, researchers embark on deciphering the structure-activity relationships inherent in these molecules, paving the way for profound insights into diseases entwined with glycosylation aberrations. The implications are far-reaching, extending to the development of novel therapeutic strategies.

Cell Culture Media: Positioned as an indispensable adjunct in cell culture media, D-mannose-[4-d] elevates cell growth and functionality to new heights. A prized supplement in cultures demanding precise control over sugar constituents to optimize cellular functions, it serves as a linchpin in studies delving into cellular metabolism and augmenting the efficacy of cell-based production systems. Researchers vouch for its efficacy in enhancing cellular performance, underscoring its indispensable role in driving scientific inquiry.

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