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D-glucitol-[4,5,6,6'-d4]

General Information
Catalog: BLP-007019
Molecular Formula: C6H10D4O6
Molecular Weight: 186.20
Chemical Structure
D-glucitol-[4,5,6,6'-d4]
Synonyms D-[4,5,6,6'-2H4]glucitol; D-[4,5,6,6'-2H4]sorbitol; D-glucitol-4,5,6,6-d4; D-[4,5,6,6'-D4]glucitol
IUPAC Name (2R,3R,4R,5S)-hexane-1,1,2,3-d4-1,2,3,4,5,6-hexaol
Related CAS 50-70-4 (unlabelled)
Solubility Soluble in DMSO, Methanol
Appearance White to Off-white Solid
Storage Store at -20°C

D-glucitol-[4,5,6,6'-d4], a deuterated form of sorbitol offering stable isotopic labeling, finds diverse applications in scientific endeavors. Here are the key applications of D-glucitol-[4,5,6,6'-d4]:

Metabolic Studies: Serving as a tracer in metabolic investigations, D-glucitol-[4,5,6,6'-d4] illuminates the pathways and conversion rates of carbohydrates within biological systems. By introducing this isotopically labeled compound, scientists navigate the intricate web of metabolic flux, unraveling the destiny of sorbitol within tissues and cells. This tool proves invaluable in the realm of diabetes research and exploration of metabolic aberrations.

NMR Spectroscopy: Tailored for nuclear magnetic resonance (NMR) spectroscopy analyses, the deuterated sorbitol variant D-glucitol-[4,5,6,6'-d4] shines as a prime candidate. The stable isotopic labeling enhances signal clarity and resolution, simplifying the deciphering of intricate spectra. Researchers delve into the molecule's structural nuances, dynamics, and interplay with biomolecules, culminating in a more precise understanding of molecular behavior.

Pharmaceutical Research: In the domain of pharmaceutical inquiry, D-glucitol-[4,5,6,6'-d4] emerges as a tool of choice for scrutinizing the pharmacokinetics and bioavailability of sorbitol-infused formulations. The deuterated iteration allows for meticulous tracking and quantification within biological milieus, facilitating the formulation of safer and more potent pharmaceutical offerings. This precision ensures optimal dosing strategies and mitigates potential side effects, ushering in a new era of pharmaceutical development.

Mass Spectrometry: Holding court as an internal standard in mass spectrometry applications, D-glucitol-[4,5,6,6'-d4] stands as a beacon for quantifying sorbitol concentrations in intricate samples. Its distinct mass signature acts as a reliable yardstick in discerning sorbitol from non-deuterated counterparts, bolstering the accuracy and sensitivity of analyses. This tool plays a pivotal role in clinical diagnostics and biochemical inquiries, offering a sharper lens into complex biological systems.

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