D-Glucitol-[5-18O]

D-Glucitol-[5-18O], a sorbitol derivative enriched with isotopic labeling, finds widespread utility in diverse research domains. Here are the key applications of D-Glucitol-[5-18O]:

Metabolic Pathway Tracing: A cornerstone of carbohydrate metabolism research, D-Glucitol-[5-18O] serves as a pivotal tool for tracing intricate metabolic pathways. By integrating this labeled compound, scientists can meticulously track its conversions and pinpoint metabolic intermediates. This unravels the dynamic interplays of metabolic fluxes and sheds light on the multifaceted roles enzymes assume within metabolic networks.

NMR and Mass Spectrometry Studies: D-Glucitol-[5-18O] emerges as a prized asset in nuclear magnetic resonance (NMR) and mass spectrometry analyses, delivering unparalleled insights into molecular architectures and quantitative assessments. The strategic isotopic labeling elevates detection sensitivity and resolution, enabling researchers to probe molecular structures and interactions with unparalleled precision.

Pharmacokinetic Studies: In the realm of drug development and pharmacokinetics, D-Glucitol-[5-18O] emerges as a potent investigative ally for unraveling the fate of related compounds within the body. By monitoring the trajectories of labeled molecules, researchers gain invaluable insights into the absorption, distribution, metabolism, and excretion dynamics of drug candidates. This data forms the bedrock for optimizing drug formulations and dosing protocols, heralding advancements in therapeutic efficacy.

Biosynthesis Research: Delving into the biosynthetic intricacies across diverse organisms, D-Glucitol-[5-18O] occupies a pivotal role in probing biosynthetic pathways, especially in the realm of sugar alcohol and metabolite production. Through meticulous tracking of its integration into metabolic products, researchers unveil the enigmatic routes and regulatory frameworks dictating biosynthesis. This knowledge serves as a linchpin for sculpting cutting-edge metabolic engineering strategies poised for transformative biotechnological applications.