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D-Lyxose-[5-18O]

General Information
Catalog: BLP-012745
Molecular Formula: C5H10O4[18O]
Molecular Weight: 152.13
Chemical Structure
D-Lyxose-[5-18O]
Synonyms D-[5-18O]lyxose; D-lyxose-5-18O; NSC 224430-5-18O; D-Lyx-5-18O; D-Lyxopyranose-5-18O; D-Lyxopyranoside-5-18O
IUPAC Name (3S,4S,5R)-tetrahydro-2H-pyran-1-18O-2,3,4,5-tetraol
Related CAS 1114-34-7 (unlabelled)
Purity ≥95%; >90% atom 18O
Solubility Soluble in Water (Slightly)
Appearance Off-white Solid
Storage Store at 2-8°C

D-Lyxose-[5-18O], a specialized isotopically labeled sugar, finds diverse applications in scientific research. Here are the key applications of D-Lyxose-[5-18O]:

Metabolic Pathway Tracing: In the realm of metabolic studies, D-Lyxose-[5-18O] serves as a valuable tracer to unravel the intricate pathways and mechanisms of carbohydrate metabolism. By introducing this labeled sugar, researchers embark on a journey to track its utilization and conversion into various metabolites, offering profound insights into the dynamic nature of metabolic networks and the precise functions of specific enzymes.

Structural Biology: Delving into the depths of structural biology, D-Lyxose-[5-18O] emerges as a pivotal tool for exploring the structures and functions of carbohydrate-binding proteins and enzymes. Through meticulous analysis of how these proteins interact with the labeled sugar, scientists unveil binding sites and intricate conformational changes. This endeavor aids in deciphering the complexities of protein-ligand interactions, laying the foundation for groundbreaking advancements in drug design and biochemistry research.

Glycoscience Research: At the forefront of glycoscience, D-Lyxose-[5-18O] stands as a potent ally for delving into glycosylation processes and the mechanisms tied to carbohydrates. Researchers harness its power to investigate the incorporation of sugars into glycoproteins or glycolipids, shedding light on the roles of these biomolecules in cellular functions. This exploration is indispensable for unraveling the mysteries of complex biological systems and discerning disease pathologies associated with glycosylation abnormalities.

Environmental Science: In the realm of environmental science, D-Lyxose-[5-18O] emerges as a key player in studying microbial metabolism and ecological interactions centered around carbohydrates. By tracing the movements and transformations of this labeled sugar within microbial communities, researchers unlock insights into nutrient cycles and the intricate web of microbial ecology. This knowledge forms the bedrock for understanding ecosystem dynamics and navigating the impacts of environmental shifts on our surroundings.

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