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D-galactitol-[6-13C]

General Information
Catalog: BLP-013323
Molecular Formula: C5[13C]H14O6
Molecular Weight: 183.16
Chemical Structure
D-galactitol-[6-13C]
Description D-galactitol-[6-13C] is an isotopic labelled analogue of D-galactitol that is the reduction product of Galactose.
Synonyms D-[6-13C]galactitol; D-[6-13C]dulcitol; D-[6-13C]dulcite; D-galactitol-6-13C; D-Euonymit-6-13C; D-Melampyrin-6-13C; D-Melampyrit-6-13C
Related CAS 608-66-2 (unlabelled)

D-galactitol-[6-13C], a labeled carbohydrate widely utilized in metabolic studies and structural biology, boasts diverse applications:

Metabolic Flux Analysis: Acting as a potent tracer in metabolic flux analysis, D-galactitol-[6-13C] aids in dissecting carbohydrate metabolism and biochemical pathways. Researchers leverage this labeled compound in metabolic experiments to track the intricate flow of carbon atoms across diverse metabolic pathways, shedding light on the dynamic intricacies and intricate regulation of metabolism across varied biological systems.

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, D-galactitol-[6-13C] emerges as a pivotal tool for exploring the structural nuances and dynamic behaviors of carbohydrates. The carbon-13 isotope serves as a robust NMR signal, furnishing comprehensive insights into the molecular structure and intricate interactions of D-galactitol. This application is vital for unraveling carbohydrate conformations and interactions at the atomic level, unraveling the intricate dance of molecular intricacies.

Glycosylation Studies: Stepping into the arena of glycosylation, D-galactitol-[6-13C] assumes a pivotal role in advancing studies on the biosynthesis and modification of glycoproteins and glycolipids. By monitoring the integration of labeled galactitol into glycan structures, researchers decipher the convoluted pathways and mechanisms of glycosylation. This aids in unraveling the multifaceted role of glycosylation in cell signaling, immune responses, and disease processes, painting a nuanced portrait of biological complexities.

Diagnostic Research: Delving into diagnostic research, D-galactitol-[6-13C] emerges as a valuable asset in crafting non-invasive tests for metabolic disorders. By detecting the labeled compound in biological samples, researchers can surveil deviations in carbohydrate metabolism, offering insights into potential abnormalities. This application proves particularly beneficial in diagnosing hereditary conditions like galactosemia and other metabolic syndromes, offering a glimpse into the intricate interplay of molecular processes shaping health and disease.

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