D-glucitol-[6-13C], a stable isotope-labeled compound of sorbitol, finds wide application in biochemical and medical fields. Here are the key applications of D-glucitol-[6-13C]:
Metabolic Tracing: Delving into metabolic pathways, researchers utilize D-glucitol-[6-13C] to trace carbohydrate metabolism in organisms. By following the labeled carbon atom, they investigate the transformation of sorbitol into diverse metabolites, unraveling intricate details of metabolic processes and fluxes.
MRI Contrast Agent: Harnessing D-glucitol-[6-13C] as a contrast agent in Magnetic Resonance Imaging (MRI) elevates imaging outcomes. The labeled carbon heightens imaging contrast, simplifying tissue visualization and distinction. This application holds significant value for non-invasive diagnostics and monitoring tissue conditions with precision.
NMR Spectroscopy: In the realm of Nuclear Magnetic Resonance (NMR) spectroscopy, D-glucitol-[6-13C] serves as an internal standard or a tracer for exploring molecular structures and interactions. The labeled isotope facilitates precise measurement of molecular dynamics and conformations, playing a critical role in structural biology and pharmaceutical research endeavors.
Pharmacokinetic Studies: Crucial for pharmacokinetic investigations, D-glucitol-[6-13C] aids in deciphering the absorption, distribution, metabolism, and excretion of sorbitol within the body. Its labeled carbon enables accurate tracking and quantification in biological samples essential for advancing drug development and ensuring safety assessments are thorough and reliable.
![D-glucitol-[6-13C]](https://resource.bocsci.com/structure/d-6-13c-glucitol.gif)
