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D-glucono-1,5-lactone-[6-13C]

General Information
Catalog: BLP-013325
Molecular Formula: C5[13C]H10O6
Molecular Weight: 179.13
Chemical Structure
D-glucono-1,5-lactone-[6-13C]
Description D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to approach a curing, pickling or leavening effect.
Synonyms D-[6-13C]glucono-1,5-lactone; D-[6-13C]gluconic acid delta-lactone
Related CAS 90-80-2 (unlabelled)

D-glucono-1,5-lactone-[6-13C], a stable isotope-labeled compound, possesses unique properties that make it invaluable for a diverse range of research applications. Here are the key applications of D-glucono-1,5-lactone-[6-13C]:

Metabolic Flux Analysis: Employing D-glucono-1,5-lactone-[6-13C] in metabolic flux analysis enables researchers to intricately trace the intricate pathways of glucose metabolism. By integrating this isotopically labeled compound into biological systems, scientists can meticulously monitor its conversion and distribution within metabolic networks, shedding light on the dynamic nuances of metabolic pathways and uncovering potential rate-limiting steps.

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, D-glucono-1,5-lactone-[6-13C] emerges as a pivotal tool for probing the structural and conformational dynamics of biomolecules. The incorporation of the 13C-labeled isotope enhances sensitivity and resolution in NMR experiments, facilitating in-depth exploration of molecular interactions and chemical environments through detailed analysis.

Biochemical Research: Delving into enzymatic reactions and their kinetics, D-glucono-1,5-lactone-[6-13C] plays a critical role in unraveling the intricate mechanisms governing enzyme action. Whether acting as a substrate or inhibitor, this compound aids in elucidating the specifics of enzyme specificity, catalytic efficiency, and regulatory mechanisms, offering researchers profound insights into the complex world of biochemical processes.

Medical Research: Extending its reach into medical research, this isotope-labeled compound proves instrumental in examining glucose metabolism in various disease contexts such as diabetes and cancer. By tracking the fate of D-glucono-1,5-lactone-[6-13C] within tissues and cells, scientists can pinpoint metabolic alterations associated with these conditions, paving the way for the development of innovative therapeutic approaches and diagnostic tools.

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