Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013143 |
Molecular Formula: [13C]6H12O6 |
Molecular Weight: 186.11 |
Chemical Structure |
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Synonyms | D-Allose-UL-13C6 |
IUPAC Name | (2R,3R,4R,5S,6R)-6-(hydroxy(1-13C)methyl)(2,3,4,5,6-13C5)oxane-2,3,4,5-tetrol |
Related CAS | 2595-97-3 (unlabelled) |
Canonical SMILES | C(C1C(C(C(C(O1)O)O)O)O)O |
InChI | InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4-,5-,6-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1 |
InChI Key | WQZGKKKJIJFFOK-HRKOKMDYSA-N |
Appearance | White Solid |
D-Allose-[1,2,3,4,5,6-13C6], a labeled monosaccharide renowned for its distinctive isotopic carbon labeling, is a staple in scientific research. Here are the key applications of D-Allose-[1,2,3,4,5,6-13C6]:
Metabolic Flux Analysis: A cornerstone of metabolic research, D-Allose-[1,2,3,4,5,6-13C6] is harnessed to unravel metabolic pathways and quantify fluxes. By integrating this labeled sugar into cellular metabolism, researchers can meticulously monitor its metamorphosis and dispersion using cutting-edge techniques like NMR or mass spectrometry. This method unveils a comprehensive comprehension of metabolic network dynamics and pinpoints potential metabolic bottlenecks.
Nutritional Studies: At the forefront of nutritional research, D-Allose-[1,2,3,4,5,6-13C6] plays a pivotal role in scrutinizing carbohydrate metabolism and absorption in living organisms. Through the administration of this isotopically labeled sugar to subjects and tracking its metabolic destiny scientists can evaluate how various carbohydrates are metabolized. This aids in shaping dietary guidelines and deciphering the metabolic ramifications of diverse sugars.
Glycobiology Research: Within the realm of glycobiology, D-Allose-[1,2,3,4,5,6-13C6] emerges as an invaluable resource for delving into glycosylation processes. Researchers leverage this labeled sugar to delve into the biosynthesis and functionality of glycoproteins and glycolipids. Unraveling these processes is paramount for unveiling the roles of glycosylation in health and disease as well as for propelling the development of glycoengineering strategies.
Drug Development: In the sphere of pharmaceutical research, D-Allose-[1,2,3,4,5,6-13C6] emerges as a potent tool for assessing the metabolism and pharmacokinetics of carbohydrate-based drugs. By tagging drug candidates with this compound scientists can monitor their metabolic trajectories and breakdown products in vivo. This intel is indispensable for refining drug design efficacy and safety measures shaping the future of pharmaceutical innovation.
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