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D-Altrose-[1-13C]

General Information
Catalog: BLP-013179
CAS: 70849-27-3
Molecular Formula: C5[13C]H12O6
Molecular Weight: 181.15
Chemical Structure
D-Altrose-[1-13C]
Synonyms (1-13C)-D-altrose; D-[1-13C]altrose
IUPAC Name (2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy(1-13C)hexanal
Related CAS 1990-29-0 (unlabelled)
Canonical SMILES C(C(C(C(C(C=O)O)O)O)O)O
InChI InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4-,5+,6-/m1/s1/i1+1
InChI Key GZCGUPFRVQAUEE-IKGLOVJPSA-N

D-Altrose-[1-13C], a stable isotope-labeled monosaccharide, is predominantly utilized in metabolic research and various analytical applications. Here are the key applications of D-Altrose-[1-13C]:

Metabolic Flux Analysis: Delving into metabolic flux analysis, D-Altrose-[1-13C] acts as a critical tool for tracing the pathways and dynamics of carbon atoms throughout metabolic networks. By monitoring the incorporation of the [1-13C] label, researchers can quantify the flow of metabolites and comprehend the kinetics of biosynthetic and degradative processes. This intricate data forms the foundation for constructing intricate metabolic models and honing metabolic engineering strategies.

NMR Spectroscopy: Embarking on nuclear magnetic resonance (NMR) spectroscopy, D-Altrose-[1-13C] emerges as a pivotal substrate employed to investigate the structure and dynamics of carbohydrates and their interactions with other biomolecules. The 13C label generates a distinctive signal in NMR spectra, facilitating precise mapping of carbon atom positions. This ability enables in-depth structural elucidation and exploration of conformational changes in intricate biological systems.

Biochemical Pathway Elucidation: D-Altrose-[1-13C] plays a crucial role in unraveling biochemical pathways, particularly shedding light on the intricacies of sugar metabolism in diverse organisms. Through incorporating the labeled Altrose into cultures and analyzing resulting metabolites, researchers pinpoint key enzymatic steps and regulatory mechanisms. This wealth of information expands our understanding of carbohydrate metabolism, potentially uncovering novel enzymes and pathways.

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