CAS 108311-21-3 D-Fructose-[1-13C] - Isotope / BOC Sciences

General Information
Catalog: BLP-013152
CAS: 108311-21-3
Molecular Formula: C5[13C]H12O6
Molecular Weight: 181.15

General Information

Catalog: BLP-013152

CAS: 108311-21-3

Molecular Formula: C5[13C]H12O6

Molecular Weight: 181.15

Chemical Structure

Description	D-Fructose-[1-13C] is an isotope labelled analogue of D-Fructose, which is a monosaccharide that naturally occurs in a large number of fruits and plants.
Synonyms	Advantose FS 95-1-13C; D-(-)-Fructose-1-13C; D-(-)-Levulose-1-13C; D-Arabino-2-hexulose-1-13C; Fructose-1-13C; Fruit Sugar-1-13C; Fujifructo L 95-1-13C; Furucton-1-13C; Hi-Fructo 970-1-13C; Krystar-1-13C; Krystar 300-1-13C; Levulose-1-13C; Nevulose-1-13C; Sugar Fruit-1-13C
IUPAC Name	(3S,4S,5R)-5-(hydroxymethyl)-2-(hydroxy(1-13C)methyl)oxolane-2,3,4-triol
Related CAS	57-48-7 (unlabelled)
Canonical SMILES	C(C1C(C(C(O1)(CO)O)O)O)O
InChI	InChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6?/m1/s1/i2+1
InChI Key	RFSUNEUAIZKAJO-BORCATHGSA-N
Melting Point	119-122°C (dec.) (lit.)
Purity	99% atom 13C

D-Fructose-[1-13C], a compound labeled with stable isotopes, is a cornerstone in metabolic research and biochemical investigations. Here are some pivotal applications of D-Fructose-[1-13C]:

Metabolic Flux Analysis: By leveraging D-Fructose-[1-13C], researchers can meticulously trace metabolic pathways and unravel the carbon flux across diverse biochemical routes. Integrating into metabolic processes, this labeled fructose enables the mapping of carbon atom destinies within intricate metabolic networks. This technique plays a fundamental role in deciphering complex diseases like diabetes and fine-tuning metabolic engineering endeavors.

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, D-Fructose-[1-13C] emerges as a vital tool for exploring the structural and dynamic attributes of carbohydrates. The distinct signal provided by the 13C label aids researchers in unraveling molecular interactions and conformations within multifaceted biological samples. This application proves particularly advantageous in the structural scrutiny of glycans and other complex biomolecules.

Tracer Studies: In the domains of clinical and nutritional exploration, D-Fructose-[1-13C] shines as a beacon serving as a tracer to investigate the absorption distribution metabolism and excretion of fructose in the human body. Through vigilant monitoring of the 13C label, scientists glean insights into fructose utilization and its implications for metabolic well-being. These studies are instrumental in unraveling dietary impacts and shaping nutritional directives.

Stable Isotope Labeling: Widely employed in labeling experiments within systems biology and synthetic biology, D-Fructose-[1-13C] empowers precise measurements of metabolic rates and the identification of metabolic intermediates in engineered biological systems. This indispensable tool facilitates the optimization of bioproduction processes and offers profound insights into cellular metabolism at a systems level fostering a comprehensive understanding of biological intricacies.