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D-Fructose-[3-d]

General Information
Catalog: BLP-012698
Molecular Formula: C6H11DO6
Molecular Weight: 181.17
Chemical Structure
D-Fructose-[3-d]
Description D-Fructose-[3-d] is the labelled analogue of D-Fructose, which is a monosaccharide that naturally occurs in a large number of fruits and plants.
Synonyms D-Fructose-3-d; D-[3-2H]fructose; Advantose FS 95-3-d; D-(-)-Fructose-3-d; D-(-)-Levulose-3-d; D-Arabino-2-hexulose-3-d; Fructose-3-d; Fruit Sugar-3-d; Fujifructo L 95-3-d; Furucton-3-d; Hi-Fructo 970-3-d; Krystar-3-d; Levulose-3-d; Nevulose-3-d
IUPAC Name (3S,4R,5R)-3-deuterio-2-(hydroxymethyl)oxane-2,3,4,5-tetrol
Related CAS 57-48-7 (unlabelled)
Canonical SMILES C1C(C(C(C(O1)(CO)O)O)O)O
InChI InChI=1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5?,6-/m0/s1/i5D
InChI Key LKDRXBCSQODPBY-BUZGMKGYSA-N
Purity ≥90%
Solubility Soluble in Water (Sparingly)
Appearance Off-white Solid
Storage Store at -20°C

D-Fructose-[3-d], a labeled variant of fructose widely utilized in biochemical and metabolic research, offers a plethora of applications. Here are the key applications:

Metabolic Flux Analysis: Acting as a tracer in metabolic flux analysis, D-Fructose-[3-d] serves as a tool to explore carbohydrate metabolism within cells and tissues. By meticulously tracking the labeled carbon atom, researchers illuminate metabolic pathways and pinpoint pivotal regulatory nodes. This knowledge is critical for unraveling the intricacies of metabolic diseases and crafting precise targeted therapies.

Glycolysis Studies: In the realm of glycolysis research, D-Fructose-[3-d] plays a crucial role in elucidating the transformation of sugars into energy. By meticulously tracing the destiny of labeled fructose, scientists quantify glycolytic intermediates and discern the enzymatic activities dictating sugar breakdown. This research is indispensable for comprehending energy generation and regulation in both physiological and pathological contexts.

Gut Microbiota Research: Delving into the metabolism of fructose by gut microbiota, D-Fructose-[3-d] offers a window into intricate fermentation processes and the generation of metabolic byproducts within the gut ecosystem. This exploration aids in deciphering the impact of dietary fructose on gut health and its interplay with metabolic disorders such as obesity and diabetes, shedding light on the complex interactions within the human microbiome.

Nutritional Studies: Within the realm of nutritional science, D-Fructose-[3-d] emerges as a key player in examining the absorption and utilization of fructose within the human body. By vigilantly monitoring the labeled fructose, researchers evaluate the efficiency of fructose digestion and its effects on blood sugar levels. This work is pivotal in shaping dietary guidelines and deepening our understanding of fructose's implications for metabolic well-being.

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