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D-Lyxose-[5-13C]

General Information
Catalog: BLP-009251
CAS: 139657-61-7
Molecular Formula: C4[13C]H10O5
Molecular Weight: 151.12
Chemical Structure
D-Lyxose-[5-13C]
Description One of the labelled D-Lyxose. D-Lyxose is the C'-2 epimer of D-xylose. It is used in molecular model calculations for drug binding and recognition studies related to aldose reductase.
IUPAC Name (2S,3S,4R)-2,3,4,5-tetrahydroxy(5-13C)pentanal
Related CAS 1114-34-7 (unlabelled)
Canonical SMILES C(C(C(C(C=O)O)O)O)O
InChI InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5-/m1/s1/i2+1
InChI Key PYMYPHUHKUWMLA-IAAYJPMJSA-N
Density 1.5±0.1 g/cm3

D-Lyxose-[5-13C], a stable isotope-labeled sugar, finds diverse utility in scientific and medical domains. Here are the key applications of D-Lyxose-[5-13C]:

Metabolic Flux Analysis: Delving into the intricate realm of metabolic flux analysis, D-Lyxose-[5-13C] serves as a potent tool for tracing the convoluted pathways of carbon within cellular systems. By meticulously monitoring the incorporation of the 13C label into metabolic intermediates, researchers unravel detailed insights into the labyrinthine world of cellular metabolism. This information plays a pivotal role in deciphering metabolic disorders and crafting innovative metabolic engineering strategies.

Biomolecular Studies: In the realm of biomolecular investigations, D-Lyxose-[5-13C] emerges as a beacon for studying the kinetics and mechanisms of carbohydrate-interacting enzymes. The discernible spectroscopic signatures afforded by the 13C label facilitate seamless tracking of enzymatic reactions, aiding researchers in unraveling the mysteries surrounding enzyme mechanisms and crafting potent inhibitors with precision.

Nutritional Research: Venturing into the realm of nutritional exploration, D-Lyxose-[5-13C] emerges as a critical asset for probing the absorption, distribution, metabolism, and excretion of sugars within physiology. By employing this labeled sugar, scientists delve into the intricate dance of different dietary carbohydrates within the body, shedding light on crucial aspects of metabolic health. This research forms the cornerstone for crafting informed dietary guidelines.

NMR Spectroscopy: Positioned at the nexus of scientific inquiry, D-Lyxose-[5-13C] emerges as a linchpin in Nuclear Magnetic Resonance (NMR) spectroscopy, offering a compelling probe to unravel the structural nuances and dynamic interplay of biomolecules. The 13C label elevates the resolution and sensitivity of NMR measurements, illuminating the conformational intricacies and subtle interactions of complex carbohydrates and other biomolecules. This application stands paramount in elucidating the molecular choreography within biological entities, pushing the boundaries of structural biology and biomolecular characterization.

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