D-mannohept-2-ulose-[1-13C]

D-mannohept-2-ulose-[1-13C], a labeled sugar molecule utilized across diverse scientific domains, particularly in metabolic and biochemical investigations, has several key applications:

Metabolic Flux Analysis: Employing D-mannohept-2-ulose-[1-13C] in metabolic flux analysis enables researchers to map out the intricate pathways and networks of carbohydrate metabolism. By integrating this labeled carbon isotope, scientists can precisely quantify the movement of carbon atoms through various biochemical routes. This deepens the comprehension of metabolic shifts in both healthy and diseased states.

NMR Spectroscopy Studies: This compound serves as a valuable asset in nuclear magnetic resonance (NMR) spectroscopy studies, facilitating the examination of the structure and dynamics of carbohydrates. The distinctive [1-13C] label generates a clear signal, simplifying the identification and exploration of individual components within complex mixtures. This aids in unraveling the molecular interactions and conformational transitions of carbohydrates within diverse biological systems.

Investigation of Glycan Biosynthesis: Scientists leverage D-mannohept-2-ulose-[1-13C] to delve into the biosynthesis and functionality of glycans, crucial components of cell membranes involved in cellular signaling. By tracing the incorporation of the labeled sugar into glycan structures, researchers glean insights into glycosylation processes. This knowledge proves vital in understanding conditions like cancer, where glycosylation patterns often undergo significant alterations.

Development of Biomarkers: In the realm of clinical diagnostics, D-mannohept-2-ulose-[1-13C] plays a pivotal role in crafting metabolic biomarkers. The distinctive labeling allows for real-time monitoring of metabolic changes in response to diseases or treatments. This application is instrumental in the early identification of diseases, tracking disease progression, and evaluating the effectiveness of therapeutic interventions.