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D-Mannose-3-[13C]

General Information
Catalog: BLP-001642
CAS: 101615-89-8
Molecular Formula: C5[13C]H12O6
Molecular Weight: 181.15
Chemical Structure
D-Mannose-3-[13C]
Description D-Mannose-3-[13C] is the labelled analogue of D-Mannose, which is a monosaccharide involved in glycosylation of some molecules in various cellular processes. Nutritional supplement in health care products.
Synonyms D-Mannopyranose-3-13C; D-[3-13C]mannose
IUPAC Name (3S,4S,5S,6R)-6-(hydroxymethyl)(4-13C)oxane-2,3,4,5-tetrol
Related CAS 3458-28-4 (unlabelled)
Canonical SMILES C(C1C(C(C(C(O1)O)O)O)O)O
InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1/i4+1
InChI Key WQZGKKKJIJFFOK-KNBZEHSBSA-N
Melting Point 133-140 °C
Purity 97% (CP); 99% atom 13C

D-Mannose-3-[13C], an isotopically labeled sugar, serves as a versatile tool in biological and medical research. Explore the key applications of D-Mannose-3-[13C]:

Metabolic Pathway Tracing: Delving into intricate metabolic pathways, D-Mannose-3-[13C] emerges as a pivotal resource for tracking the incorporation and metabolism of mannose within cells. By meticulously monitoring the labeled carbon atom, researchers unveil the enigmatic processes underlying mannose metabolism, shedding light on its profound impacts on cellular function and disease progression.

Glycoprotein and Glycolipid Research: In the realm of cellular exploration, scientists turn to this labeled sugar to unravel the enigmatic world of glycoproteins and glycolipids – essential components of cell membranes and signaling cascades. By integrating D-Mannose-3-[13C] into these intricate biomolecules, researchers embark on a journey to elucidate their synthesis, structure, and functional roles, unraveling the complexities of cellular communication pathways and guiding the development of innovative therapeutic strategies.

Disease Mechanism Studies: At the forefront of investigative endeavors, D-Mannose-3-[13C] stands as a cornerstone in unraveling the mechanisms underlying metabolic disorders and infectious diseases. By leveraging this invaluable resource, researchers dissect complex disorders such as congenital disorders of glycosylation (CDG) where disruptions in mannose metabolism occur. Furthermore, exploring how pathogens manipulate host carbohydrate pathways opens doors for targeted therapeutic interventions, shaping the future of disease management.

Biomarker Discovery: In the clinical landscape, the isotopically labeled D-Mannose-3-[13C] emerges as a potent tool for unearthing and quantifying biomarkers in biological samples. Through intricate metabolic labeling experiments, researchers unveil diagnostic markers of diseases, advancing clinical diagnostics. By deciphering the incorporation patterns and metabolic pathways of D-Mannose-3-[13C], scientists gain profound insights into disease states and progression, revolutionizing the field of biomarker discovery.

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