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D-Mannose-6-[13C]

General Information
Catalog: BLP-001643
CAS: 115973-81-4
Molecular Formula: C5[13C]H12O6
Molecular Weight: 181.15
Chemical Structure
D-Mannose-6-[13C]
Description D-Mannose-6-[13C] is the labelled analogue of D-Mannose, which is a monosaccharide involved in glycosylation of some molecules in various cellular processes. Nutritional supplement in health care products.
Synonyms (6-13C)mannose; D-Mannose-6-13C
IUPAC Name (3S,4S,5S,6R)-6-(hydroxy(1-13C)methyl)oxane-2,3,4,5-tetrol
Related CAS 3458-28-4 (unlabelled)
Canonical SMILES C(C1C(C(C(C(O1)O)O)O)O)O
InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1/i1+1
InChI Key WQZGKKKJIJFFOK-JKTQHQGQSA-N
Melting Point 133 °C
Purity 99% (CP); 99% atom 13C

D-Mannose-6-[13C], a carbon-labeled sugar molecule, finds diverse applications in scientific research. Here are the key applications:

Metabolic Pathway Tracking: In the realm of metabolic research, D-Mannose-6-[13C] serves as a valuable tool for tracing the incorporation and utilization of mannose within cellular pathways. Through carbon isotope labeling, researchers can meticulously track the metabolic destiny of mannose in processes like glycolysis and glycosylation. This profound understanding aids in unraveling metabolic disorders and enhancing efforts in metabolic engineering to shape the future of biotechnology.

Glycoprotein Synthesis Studies: Delving into the intricate field of glycobiology, D-Mannose-6-[13C] plays a pivotal role in unraveling the mystery of glycoprotein biosynthesis. By integrating the labeled mannose into glycoproteins, scientists embark on a journey to decipher the intricate functions of various enzymes in glycan assembly. This application is absolutely critical for shedding light on diseases linked to glycosylation anomalies while paving the way for groundbreaking therapeutic interventions that hold the promise of transforming healthcare.

Nutritional Research: Exploring the realm of nutritional research, D-Mannose-6-[13C] emerges as a powerful tool for studying the absorption and metabolism of dietary mannose within the human body. Through meticulous tracking of labeled mannose, researchers gather crucial insights into its impact on gut health and potential therapeutic benefits in combating urinary tract infections. This knowledge fuels the development of precisely targeted nutritional supplements and therapeutic strategies that hold the potential to revolutionize healthcare practices.

Pharmaceutical Development: In the domain of pharmaceutical innovation, D-Mannose-6-[13C] emerges as a game-changer offering a unique tracer for studying the pharmacokinetics and biodistribution of mannose-containing drugs. By incorporating the labeled mannose into drug formulations, scientists gain unprecedented insights into the delivery and metabolism of these drugs in vivo, laying the groundwork for optimizing drug design and enhancing therapeutic efficacy. This information is indispensable for advancing the realms of drug development and improving patient outcomes.

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