Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-006066 |
Molecular Formula: C5H7D4NO2S |
Molecular Weight: 153.24 |
Chemical Structure |
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Description | D-Methionine-3,3,4,4-d4 is a labelled D-Methionine. Methionine is an α-amino acid essential for humans. Methionine plays a role in angiogenesis. |
Synonyms | (R)-Methionine-d4; MRX 1024-d4; NSC 45689-d4; S-Methyl-D-homocysteine-d4; D-Methionine D4; (R)-2-Amino-4-(methylthio)butyric Acid-d4; H-D-Met-OH-d4 |
IUPAC Name | (2R)-2-amino-3,3,4,4-tetradeuterio-4-methylsulfanylbutanoic acid |
Related CAS | 348-67-4 (unlabelled) |
Canonical SMILES | CSCCC(C(=O)O)N |
InChI | InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1/i2D2,3D2 |
InChI Key | FFEARJCKVFRZRR-LZGMMHEISA-N |
Melting Point | >193°C (dec.) |
Purity | 95% by CP; 98% atom D |
Solubility | Soluble in Water |
Appearance | White Solid |
Storage | Store at-20°C |
D-Methionine-[d4] is a stable isotope-labeled form of the amino acid methionine used in various research and industrial applications. Here are some key applications of D-Methionine-[d4:
Metabolic Research: D-Methionine-[d4] is widely used in metabolic studies to trace methionine metabolism and its incorporation into proteins. By providing a distinguishable marker, this compound allows researchers to track metabolic pathways and understand methionine’s role in cellular processes. This is crucial in exploring metabolic disorders and developing targeted therapeutic interventions.
Proteomics: In proteomics, D-Methionine-[d4] is used as an internal standard in mass spectrometry to quantify methionine-containing peptides accurately. This isotopic labeling helps in identifying and quantifying proteins, enabling a deeper understanding of protein expression and post-translational modifications. The precision offered by D-Methionine-[d4] enhances the reliability of proteomics research.
Nutritional Studies: D-Methionine-[d4] is employed to study the bioavailability and utilization of methionine in biological systems. By using this labeled molecule, scientists can assess how dietary methionine is absorbed, distributed, and utilized in various tissues. This information is valuable for optimizing nutritional formulations and understanding methionine’s role in health and disease.
Chemical Synthesis: D-Methionine-[d4] is used in the synthesis of deuterated compounds for research and industrial applications. Its stable isotope labeling facilitates the development of novel drug compounds and the study of reaction mechanisms. Additionally, it can be used as a precursor in the synthesis of complex molecules, contributing to advancements in pharmaceutical chemistry.
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