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D-arabinitol-[13C5]

General Information
Catalog: BLP-008114
Molecular Formula: [13C]5H12O5
Molecular Weight: 157.11
Chemical Structure
D-arabinitol-[13C5]
Description Isotope labelled analogue of D-arabinitol, a sugar alcohol. D-arabinitol was used as a diagnostic tool for the detection of fungal infections in neutropenic patients.
Synonyms D-[UL-13C5]arabinitol; D-arabinitol 13C5
IUPAC Name (2R,4R)-pentane-1,2,3,4,5-pentaol-1,2,3,4,5-13C5
Related CAS 488-82-4 (unlabelled)
Melting Point 99-101°C
Purity 98% by CP; 98% atom 13C
Solubility Soluble in DMSO, Methanol, Water
Appearance White Solid
Storage Store at -20°C

D-arabinitol-[13C5], a stable isotope-labeled compound widely utilized in diverse bioscience applications, holds pivotal roles in various key applications. Here are some applications of D-arabinitol-[13C5]:

Metabolic Flux Analysis: By incorporating the isotopically labeled carbon atoms of D-arabinitol-[13C5] into metabolic intermediates, researchers can trace the metabolic pathways within biological systems. Monitoring the distribution of this labeled compound enables a real-time exploration of metabolic flux dynamics. This detailed analysis is essential for unraveling the intricate metabolic changes associated with diseases or metabolic engineering strategies.

Quantitative P+roteomics: Within quantitative proteomics, D-arabinitol-[13C5] serves as an internal standard for ensuring precise measurement of protein concentrations. Integrating the labeled compound into proteomic samples facilitates accurate quantification and comparison of protein levels. This technique is paramount for identifying differentially expressed proteins and deciphering their roles in diverse biological processes.

Research on Carbohydrate Metabolism: As a valuable tool in the study of carbohydrate metabolism across various organisms, D-arabinitol-[13C5] aids researchers in comprehending the roles and fates of sugar alcohols within different biological contexts. Its inclusion in metabolic studies provides insights into how specific enzymes interact with the labeled D-arabinitol, shedding light on enzyme kinetics and metabolic regulations.

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