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α-D-glucopyranosyl 1-phosphate-[UL-13C6] dipotassium salt hydrate

General Information
Catalog: BLP-012711
Molecular Formula: H11[13C]6K2O9P.x(H2O)
Molecular Weight: 342.27 (Anhydrous)
Chemical Structure
α-D-glucopyranosyl 1-phosphate-[UL-13C6] dipotassium salt hydrate
Synonyms alpha-D-[UL-13C6]Glc1P dipotassium salt hydrate; alpha-D-[UL-13C6]glucose 1-phosphate dipotassium salt hydrate; α-D-[UL-13C6]glucopyranosyl 1-phosphate dipotassium salt hydrate
IUPAC Name dipotassium;[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-13C6 phosphate;hydrate
Related CAS 6736-77-2 (unlabelled anhydrous) 59-56-3 (unlabelled free base)
Purity ≥98%; ≥98% atom 13C

α-D-Glucopyranosyl 1-phosphate-[UL-13C6] dipotassium salt hydrate, a specialized isotope-labeled compound, finds diverse applications in bioscience. Here are the key applications:

Metabolic Flux Analysis: Widely utilized for tracing and quantifying metabolic pathways in cellular systems, α-D-glucopyranosyl 1-phosphate-[UL-13C6] facilitates the examination of glucose-derived carbon atom flow in metabolic studies. This aids in deciphering metabolic dynamics and pinpointing pivotal regulatory nodes crucial to cellular metabolism.

Enzyme Mechanism Studies: In the realm of biochemical research, α-D-glucopyranosyl 1-phosphate-[UL-13C6] plays a crucial role in unraveling the mechanisms of enzymes engaged in carbohydrate metabolism. By employing this labeled substrate, scientists can meticulously track enzymatic reactions and ascertain kinetic parameters with remarkable precision, shedding light on enzyme functionality and aiding in the development of enzyme inhibitors.

Glycogen Biosynthesis Research: Particularly valuable in investigations focused on glycogen biosynthesis and glycogen storage disorders, this compound provides insights into the regulation of glycogen synthesis by tracing the incorporation of isotope-labeled glucose into glycogen. This knowledge is vital for comprehending and addressing metabolic ailments associated with glycogen storage.

Stable Isotope-Resolved Metabolomics: A potent tool in metabolomics, α-D-glucopyranosyl 1-phosphate-[UL-13C6] aids in resolving metabolic pathways using stable isotope labeling. By monitoring the destiny of labeled glucose, researchers can delineate complex metabolic networks and uncover metabolite fluxes across diverse biological contexts. This technique advances our comprehension of cellular metabolism and its alterations in pathological conditions.

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