D-glucuronic acid-[UL-13C6] sodium salt monohydrate

D-glucuronic acid-[UL-13C6] sodium salt monohydrate, a widely utilized labeled compound in biochemical and pharmaceutical research, finds diverse applications. Here are the key applications of this compound:

Metabolic Pathway Tracing: Serving as a tracer in metabolic investigations, D-glucuronic acid-[UL-13C6] sodium salt monohydrate sheds light on the intricate glucuronidation pathway. By integrating this isotopically labeled entity, researchers can meticulously monitor the metabolic journey of glucuronic acid within biological systems, unraveling metabolic intricacies and pinpointing metabolic byproducts.

Pharmacokinetics: In the realm of pharmacology, D-glucuronic acid-[UL-13C6] sodium salt monohydrate serves as a powerful tool for delving into the pharmacokinetics of drugs subject to glucuronidation. Leveraging this labeled analog, scientists can ascertain the kinetics of drug conjugation, metabolism, and excretion—crucial insights that drive drug refinement and dosing regimen optimization.

Enzyme Activity Studies: Unlocking the secrets of enzyme dynamics in the glucuronidation cascade, D-glucuronic acid-[UL-13C6] sodium salt monohydrate facilitates the evaluation of enzyme activity. By furnishing a labeled substrate, researchers can delve into enzyme kinetics, identifying potential modulators of enzymatic function. This exploration is instrumental in deciphering enzyme behavior and its regulation across diverse physiological and pathological contexts.

Environmental Toxicology: Venturing into the realm of environmental toxicology, this compound serves as a cornerstone in scrutinizing the biotransformation of environmental contaminants. By delving into the metabolization patterns of these pollutants, researchers can gauge the associated risks and long-term repercussions of exposure, informing strategies for pollution mitigation and environmental remediation efforts.