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D-idose-[UL-13C6]

General Information
Catalog: BLP-013336
Molecular Formula: [13C]6H12O6
Molecular Weight: 186.11
Chemical Structure
D-idose-[UL-13C6]
Description D-idose-[UL-13C6] is a stable labelled analogue of D-idose, a monosaccharide that is an important component of dermatan sulfate and heparan sulfate.
Synonyms D-[UL-13C6]idose; D-idose-U-13C6
Related CAS 5978-95-0 (unlabelled)

D-idose-[UL-13C6], a uniformly labeled carbon-13 sugar, finds diverse applications in bioscience. Here are the key applications of D-idose-[UL-13C6]:

Metabolic Flux Analysis: In the realm of metabolic flux analysis, D-idose-[UL-13C6] plays a vital role in elucidating carbon pathways within cellular metabolism. By integrating this labeled sugar into cells, researchers can trace the distribution of carbon atoms across various metabolic networks. This method enables a deeper comprehension of cellular metabolism, energy production, and the repercussions of genetic alterations.

NMR Spectroscopy: The uniform labeling of D-idose-[UL-13C6] proves invaluable in nuclear magnetic resonance (NMR) spectroscopy investigations. This compound facilitates the examination of metabolic intermediates and products with high resolution. By utilizing D-idose-[UL-13C6], scientists can gain profound insights into the structural and dynamic characteristics of biomolecules, opening doors to new discoveries.

Stable Isotope Tracing: Serving as a stable isotope tracer in biochemical research, D-idose-[UL-13C6] offers a powerful tool for studying metabolic processes. By leveraging this compound, researchers can delve into the incorporation and conversion of labeled carbon atoms, shedding light on metabolic pathways, enzyme activities, and the impacts of various interventions on cellular metabolism. This technique is indispensable for unraveling the complexities of biological systems.

Glycosylation Research: In the field of glycosylation studies, D-idose-[UL-13C6] serves as a key player in exploring the biosynthesis and modification of glycoconjugates. Incorporating this labeled sugar into glycoproteins or glycolipids enables scientists to track and analyze glycosylation patterns with precision. This knowledge is crucial for unveiling the functional roles of glycosylation in both health and disease, paving the way for groundbreaking advancements in medical research.

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