D-mannose-[UL-13C6] 6-phosphate disodium salt

D-mannose-[UL-13C6] 6-phosphate disodium salt, a compound extensively utilized in biochemical and metabolic studies, plays a pivotal role in various scientific investigations. Here are the key applications of D-mannose-[UL-13C6] 6-phosphate disodium salt:

Metabolic Flux Analysis: This labeled compound is a cornerstone in metabolic flux analysis, enabling the tracing of carbohydrate metabolism pathways. By introducing [13C] isotopes, researchers can meticulously follow the conversion steps of mannose-6-phosphate within intricate metabolic networks. This method sheds light on the dynamic interplay and regulation of metabolic pathways across diverse biological systems.

Glycosylation Studies: D-mannose-[UL-13C6] 6-phosphate disodium salt is indispensable for delving into glycosylation pathways, where sugars are intricately attached to proteins or lipids. Leveraging isotopically labeled mannose-6-phosphate, scientists can monitor its integration into glycoproteins and glycolipids, unraveling crucial insights into disorders stemming from aberrant glycosylation processes.

Diagnostic Biomarker Research: In the realm of diagnostic biomarker research, this compound serves as a valuable tool for investigating metabolic disorders. By meticulously tracing the labeled compound through metabolic pathways, researchers can pinpoint anomalies in mannose metabolism, facilitating the identification of conditions like congenital disorders of glycosylation. This approach holds promise for enhancing diagnostic accuracy and therapeutic interventions.

Enzyme Kinetics: D-mannose-[UL-13C6] 6-phosphate disodium salt is a key player in deciphering enzyme kinetics, aiding in the comprehension of enzyme activity and specificity within mannose metabolism. Researchers can quantify the interaction between enzymes and the labeled substrate, yielding intricate kinetic parameters crucial for drug development targeting metabolic enzymes. This knowledge serves as a foundational pillar in advancing precision medicine and therapeutic research initiatives.