| Description |
Desonide-[13C3] is the labelled analogue of Desonide. Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, psoriasis and contact dermatitis in both adults and children and has a fairly good safety profile and is available as a cream, ointment, lotion. |
| Synonyms |
[13C3]-Desonide; (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene-13C3)bis(oxy)]pregna-1,4-diene-3,20-dione; 16α-Hydroxyprednisolone Acetonide-13C3; Locapred-13C3; Topifug-13C3; Tridesilon-13C3; Desonide-13C3 |
| IUPAC Name |
(6aR,7S,8aS,8bS,11aR,12bR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10,10-di(methyl-13C)-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one-10-13C |
| Related CAS |
638-94-8 (unlabelled)
|
| Canonical SMILES |
CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C)C |
| InChI |
InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16?,17-,19+,20?,22-,23-,24+/m0/s1/i1+1,2+1,21+1 |
| InChI Key |
WBGKWQHBNHJJPZ-FGIIUYPESA-N |
| Melting Point |
159-163 °C |
| Purity |
97%; 97% atom 13C |
| Solubility |
Slightly soluble in DMF, DMSO, Methanol |
| Appearance |
Off-white to Pale Yellow Solid |
| Storage |
2-8 °C |
![Desonide-[13C3]](/isotope.v1/images/structure-default.jpg)
