| Description |
Dexamethasone-[d5] is the labelled analogue of Dexamethasone, which is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation and inhibits the induction of nitric oxide synthase. |
| Synonyms |
Dexamethasone-D5; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-pregna-1,4-diene-3,20-dione-d5; 16α-Methyl-9α-fluoroprednisolone-d5; Aeroseb-Dex-d5; Corson-d5; Cortisumman-d5; Decacort-d5; Decaderm-d5; Decadron-d5; Decalix-d5; Decasone-d5; Dekacort-d5 |
| IUPAC Name |
(8S,9R,10S,11S,13S,14S,16R,17R)-4,6,6-trideuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthren-3-one |
| Related CAS |
50-02-2 (unlabelled)
|
| Isomeric SMILES |
[2H]C1=C2[C@](C=CC1=O)([C@]3([C@H](C[C@]4([C@H]([C@@H]3CC2([2H])[2H])C[C@H]([C@@]4(C(=O)C([2H])([2H])O)O)C)C)O)F)C |
| Canonical SMILES |
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C |
| InChI |
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1/i4D2,9D,11D2 |
| InChI Key |
UREBDLICKHMUKA-QEPYKOQPSA-N |
| Melting Point |
230-232°C |
| Purity |
≥95%; ≥96% atom D |
| Solubility |
Soluble in Dioxane (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance |
Off-white to Pale Yellow Solid |
| Storage |
Store at -20°C |
![Dexamethasone-[d5]](https://resource.bocsci.com/structure/358731-91-6.gif)
