Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-005145 |
CAS: 1246818-62-1 |
Molecular Formula: C10H9D3N2 |
Molecular Weight: 163.24 |
Chemical Structure |
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Description | Dihydro Nicotyrine-[d3] is a deuterium labelled form of Dihydro Nicotyrine, which is a metabolite of Nicotyrine. |
Synonyms | 3-(4,5-Dihydro-1-[(methyl-d3)-1H-pyrrol-2-yl)]pyridine; 3-[4,5-Dihydro-1-(methyl-d3)pyrrol-2-yl]pyridine; N-Methylmyosmine-d3; Dihydro Nicotyrine D3 |
IUPAC Name | 3-[1-(trideuteriomethyl)-2,3-dihydropyrrol-5-yl]pyridine |
Related CAS | 525-74-6 (unlabelled) |
Canonical SMILES | CN1CCC=C1C2=CN=CC=C2 |
InChI | InChI=1S/C10H12N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4-6,8H,3,7H2,1H3/i1D3 |
InChI Key | TVKHGXPZBZKXFM-FIBGUPNXSA-N |
Boiling Point | 301.8±41.0°C at 760 mmHg |
Density | 1.1±0.1 g/cm3 |
Solubility | Soluble in Chloroform |
Appearance | Pale Yellow Oil |
Storage | Store at-86°C |
Dihydro Nicotyrine-[d3], a stable isotope-labeled compound utilized in research settings, finds diverse applications in analytical scenarios. Here are key applications of Dihydro Nicotyrine-[d3] presented with high perplexity and burstiness:
Pharmacokinetic Studies: Acting as an internal standard in pharmacokinetic investigations, Dihydro Nicotyrine-[d3] aids in analyzing the absorption, distribution, metabolism, and excretion (ADME) of nicotyrine compounds. By leveraging a deuterium-labeled variant, researchers can meticulously trace and quantify the pharmacokinetics of nicotyrine in biological samples, yielding crucial data for therapeutic agent development.
Metabolomics: In the realm of metabolomics research, Dihydro Nicotyrine-[d3] assumes the role of a reference compound, facilitating the identification and quantification of metabolites within complex biological matrices. Serving as a dependable standard for mass spectrometry-based assays, it enhances the precision and accuracy of metabolic profiling. This functionality enables researchers to delve deeper into metabolic pathways and their deviations in various disease contexts.
Toxicological Studies: Employed in investigating the potential toxicity and biological interactions of related compounds, Dihydro Nicotyrine-[d3] acts as a labeled analog in experimental models. Researchers utilize this compound to explore the toxicological impacts and ascertain safe dosage levels of nicotyrine derivatives. Such insights are paramount for risk evaluation and the formulation of safe pharmaceutical products.
Biomarker Development: Within the realm of biomarker exploration, Dihydro Nicotyrine-[d3] plays a pivotal role in discovering and validating novel biomarkers for disease diagnosis and surveillance. Through its stable isotope label, it enables precise quantification of nicotyrine-related biomarkers in diagnostic assays. These applications streamline the early detection and improved management of diseases through accurate biomarker evaluation.
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