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Dihydro Nicotyrine-[d3]

General Information
Catalog: BLP-005145
CAS: 1246818-62-1
Molecular Formula: C10H9D3N2
Molecular Weight: 163.24
Chemical Structure
Dihydro Nicotyrine-[d3]
Description Dihydro Nicotyrine-[d3] is a deuterium labelled form of Dihydro Nicotyrine, which is a metabolite of Nicotyrine.
Synonyms 3-(4,5-Dihydro-1-[(methyl-d3)-1H-pyrrol-2-yl)]pyridine; 3-[4,5-Dihydro-1-(methyl-d3)pyrrol-2-yl]pyridine; N-Methylmyosmine-d3; Dihydro Nicotyrine D3
IUPAC Name 3-[1-(trideuteriomethyl)-2,3-dihydropyrrol-5-yl]pyridine
Related CAS 525-74-6 (unlabelled)
Canonical SMILES CN1CCC=C1C2=CN=CC=C2
InChI InChI=1S/C10H12N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4-6,8H,3,7H2,1H3/i1D3
InChI Key TVKHGXPZBZKXFM-FIBGUPNXSA-N
Boiling Point 301.8±41.0°C at 760 mmHg
Density 1.1±0.1 g/cm3
Solubility Soluble in Chloroform
Appearance Pale Yellow Oil
Storage Store at-86°C

Dihydro Nicotyrine-[d3], a stable isotope-labeled compound utilized in research settings, finds diverse applications in analytical scenarios. Here are key applications of Dihydro Nicotyrine-[d3] presented with high perplexity and burstiness:

Pharmacokinetic Studies: Acting as an internal standard in pharmacokinetic investigations, Dihydro Nicotyrine-[d3] aids in analyzing the absorption, distribution, metabolism, and excretion (ADME) of nicotyrine compounds. By leveraging a deuterium-labeled variant, researchers can meticulously trace and quantify the pharmacokinetics of nicotyrine in biological samples, yielding crucial data for therapeutic agent development.

Metabolomics: In the realm of metabolomics research, Dihydro Nicotyrine-[d3] assumes the role of a reference compound, facilitating the identification and quantification of metabolites within complex biological matrices. Serving as a dependable standard for mass spectrometry-based assays, it enhances the precision and accuracy of metabolic profiling. This functionality enables researchers to delve deeper into metabolic pathways and their deviations in various disease contexts.

Toxicological Studies: Employed in investigating the potential toxicity and biological interactions of related compounds, Dihydro Nicotyrine-[d3] acts as a labeled analog in experimental models. Researchers utilize this compound to explore the toxicological impacts and ascertain safe dosage levels of nicotyrine derivatives. Such insights are paramount for risk evaluation and the formulation of safe pharmaceutical products.

Biomarker Development: Within the realm of biomarker exploration, Dihydro Nicotyrine-[d3] plays a pivotal role in discovering and validating novel biomarkers for disease diagnosis and surveillance. Through its stable isotope label, it enables precise quantification of nicotyrine-related biomarkers in diagnostic assays. These applications streamline the early detection and improved management of diseases through accurate biomarker evaluation.

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