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DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate

General Information
Catalog: BLP-009859
CAS: 157203-91-3
Molecular Formula: C4H7D4NO6S
Molecular Weight: 187.21
Chemical Structure
DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate
Description DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate is a labelled DL-Homocysteic acid. Homocysteic acid is a metabolite of homocysteine and an agonist of NMDA receptor.
Synonyms DL-Homocysteic-3,3,4,4-d4 Acid H2O; (±)-2-Amino-4-sulfobutyric Acid-d4 H2O
Related CAS 504-33-6 (unlabelled)
Purity 95% by HPLC; 98% atom D

DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate, a deuterated variant of homocysteic acid, finds diverse applications in research and diagnostics. Here are the key applications:

Neuroscience Research: In the realm of neuroscience, DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate emerges as a vital tool for exploring the functions of homocysteic acid within the central nervous system. This compound serves as a linchpin in unraveling excitotoxicity, a phenomenon intricately linked to neurodegenerative disorders like Alzheimer’s and Parkinson’s. With its deuterated nature, it facilitates precise monitoring and quantification in metabolic investigations, offering a gateway to deeper insights.

Metabolic Studies: Scientists leverage DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate to delve into the intricacies of sulfur-containing amino acid pathways, particularly in the metabolic cascades of methionine and cysteine. The isotope labeling feature not only disentangles homocysteic acid from other metabolites but also enables nuanced analysis of metabolic pathways. This nuanced approach fosters a comprehensive understanding of metabolic interactions and dynamics.

Isotope Dilution Analysis: A cornerstone in quantitative mass spectrometry, this deuterated compound plays a pivotal role in isotope dilution analysis. By acting as an internal standard, it ensures precise quantification of homocysteic acid levels in biological specimens. This technique, instrumental in diagnostic protocols and biomarker exploration, sets a gold standard for accuracy and reliability in quantitative analyses.

Pharmacokinetics: DL-Homocysteic Acid-[3,3,4,4-d4] monohydrate emerges as a linchpin in pharmacokinetic inquiries, shedding light on its distribution, metabolism, and elimination within living organisms. The deuterium labeling aspect facilitates meticulous measurements of this compound in complex biological matrices, enabling a thorough grasp of its behavior within biological systems. Such insights are indispensable for evaluating the efficacy and safety profiles of potential therapeutic interventions targeting associated pathways.

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