DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl

DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl, a labeled amino acid, finds diverse applications in scientific research. Here are the key applications of DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl:

Metabolic Flux Analysis: Delving into metabolic flux analysis, researchers utilize DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl to trace the intricate pathways of lysine metabolism within cellular systems. By introducing this labeled precursor into cells, scientists can meticulously track its conversion into various metabolites, allowing for the comprehensive mapping of lysine metabolic processes and the dynamic interplay of cellular metabolism.

Proteomics: Playing a pivotal role in proteomics endeavors, this labeled lysine is indispensable in methodologies such as stable isotope labeling by amino acids in cell culture (SILAC). DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl enables precise quantification of protein abundance and dynamics in complex biological samples, facilitating the identification of potential biomarkers and the exploration of intricate protein-protein interactions within cellular systems.

Protein Turnover Studies: Researchers harness DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl to investigate the turnover rates of proteins in cellular and tissue contexts. By monitoring its integration into newly synthesized proteins, scientists can quantify the rates of protein synthesis and degradation, offering crucial insights into the underlying cellular mechanisms governing growth, development, and disease progression.

In Vivo Tracing: In the realm of in vivo studies, DL-Lysine-[2,3,3,4,4,5,5,6,6-d9] 2HCl serves as a valuable tool for tracing lysine metabolism and utilization across diverse tissues within model organisms. Administered to these organisms, this labeled compound sheds light on the distribution and metabolic fate of lysine in various organs, providing valuable insights into disorders related to amino acid metabolism and the nuanced nutritional requirements of living organisms.