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DL-Methionine-[13C5,d8,15N]

General Information
Catalog: BLP-008128
Molecular Formula: [13C]5H3D8[15N]O2S
Molecular Weight: 163.22
Chemical Structure
DL-Methionine-[13C5,d8,15N]
Description DL-Methionine-[13C5,d8,15N] is a labelled DL-Methionine. Methionine is an α-amino acid essential for humans. Methionine plays a role in angiogenesis.
Synonyms DL-Methionine 13C5,D8,15N; L-Methionine-13C5,15N,2,3,3,4,4-d5-(methyl-d3)
IUPAC Name 2-(15N)azanyl-2,3,3,4,4-pentadeuterio-4-(trideuterio(1-13C)methylsulfanyl)(1,2,3,4-13C4)butanoic acid
Related CAS 59-51-8 (unlabelled)
Canonical SMILES CSCCC(C(=O)O)N
InChI InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i1+1D3,2+1D2,3+1D2,4+1D,5+1,6+1
InChI Key FFEARJCKVFRZRR-QVISGHFZSA-N
Purity 98% by CP; 97% atom 13C; 97% atom D; 97% atom 15N
Storage Store at -20°C

DL-Methionine-[13C5,d8,15N], a labeled amino acid utilized in diverse advanced scientific research endeavors, embodies high perplexity and burstiness in its key applications:

Metabolic Flux Analysis: Serving as a tracer in metabolic flux analysis, DL-Methionine-[13C5,d8,15N] plays a pivotal role in elucidating the dynamic intricacies of cellular metabolism. By integrating this labeled compound into metabolic pathways, researchers can meticulously monitor its incorporation into various metabolites. This methodology facilitates comprehension of metabolic shifts under diverse physiological settings and stress conditions, offering a nuanced perspective on cellular function.

Proteomics: Essential in proteomic investigations employing mass spectrometry, DL-Methionine-[13C5,d8,15N] enables precise quantification and identification of proteins by introducing stable isotopes into the amino acid sequence. This methodology allows for in-depth exploration of protein dynamics, including turnover rates, post-translational modifications, and differential expression within complex biological samples. The utilization of DL-Methionine-[13C5,d8,15N] elevates the depth of proteomic analysis and enriches our understanding of intricate biological processes.

Nutritional Studies: In the realm of nutritional research, DL-Methionine-[13C5,d8,15N] serves as a valuable tool for tracking and measuring the assimilation and metabolism of methionine in both animal and human studies. By administering this labeled compound, scientists can delve into methionine’s contributions to growth, development, and disease states. This research not only aids in optimizing dietary formulations but also enhances our comprehension of essential amino acid requirements for overall health and well-being.

Environmental Studies: Positioned at the intersection of ecological and environmental research, DL-Methionine-[13C5,d8,15N] assists in tracing nutrient cycling and organic matter turnover in ecosystems. By following the labeled amino acid through various trophic levels, researchers can unravel the intricate interplay within food webs, shedding light on ecosystem dynamics and the impacts of environmental changes. This application underscores the crucial role DL-Methionine-[13C5,d8,15N] plays in advancing our understanding of ecosystem functioning and resilience in the face of environmental challenges.

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