Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-008130 |
Molecular Formula: C5H6D7ClN2O2 |
Molecular Weight: 175.66 |
Chemical Structure |
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Description | DL-Ornithine-[d7] Hydrochloride is a labelled DL-Ornithine. Ornithine is an α-amino acid produced in the urea cycle from arginine. |
Synonyms | DL-Ornithine HCl D7 |
IUPAC Name | 2,5-diamino-2,3,3,4,4,5,5-heptadeuteriopentanoic acid;hydrochloride |
Related CAS | 1069-31-4 (unlabelled) |
Canonical SMILES | C(CC(C(=O)O)N)CN.Cl |
InChI | InChI=1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/i1D2,2D2,3D2,4D; |
InChI Key | GGTYBZJRPHEQDG-HVAXMCRXSA-N |
Purity | 95% by CP; 98% atom D |
Storage | Store at -20°C |
DL-Ornithine-[d7] Hydrochloride, a stable isotope-labeled compound with diverse applications in scientific and medical domains, is an indispensable tool for cutting-edge research. Here are the key applications:
Metabolic Studies: Positioned at the forefront of metabolic flux analysis, DL-Ornithine-[d7] Hydrochloride serves as a pivotal tracer in unraveling the intricacies of metabolic pathways. By integrating this labeled compound into metabolic processes, researchers can meticulously track and quantify the rates of metabolic reactions. This invaluable data not only enhances our comprehension of metabolic disorders but also plays a crucial role in refining metabolic engineering strategies, paving the way for innovative advancements in the field.
Proteomics Research: In the realm of proteomics, DL-Ornithine-[d7] Hydrochloride emerges as a powerful tool for probing protein turnover and degradation dynamics. Through the incorporation of labeled amino acids into proteins, scientists can monitor the synthesis and breakdown rates of proteins using advanced mass spectrometry techniques. This application sheds light on protein dynamics and reveals the intricate regulatory mechanisms governing diverse cellular processes, offering unparalleled insights into cellular function and behavior.
Pharmacokinetics: At the intersection of pharmacology and kinetics, DL-Ornithine-[d7] Hydrochloride plays a pivotal role in elucidating the disposition and fate of drugs within the body. By employing labeled ornithine, researchers can meticulously track the absorption, distribution, metabolism, and excretion (ADME) of drugs, tracing their metabolic pathways and interactions within the biological milieu. This comprehensive understanding of drug metabolism not only informs therapeutic regimens but also drives advancements in drug development and personalized medicine, revolutionizing the landscape of pharmaceutical research.
Nutritional Science: Within the realm of nutritional science, DL-Ornithine-[d7] Hydrochloride emerges as a cornerstone for investigating amino acid metabolism and requirements across diverse organisms. Harnessing the power of stable isotope labeling, researchers can precisely quantify the utilization and conversion of ornithine in various tissues, shedding light on the intricate dynamics of amino acid metabolism. This data not only informs the development of nutritional guidelines but also advances our understanding of amino acid-related health challenges, laying the foundation for tailored interventions and improved health outcomes.
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