DL-Proline-[4-13C]

DL-Proline-[4-13C], a stable isotope-labeled amino acid, finds diverse applications in research and industry. Here are key applications presented with high perplexity and burstiness:

Metabolic Flux Analysis: Leveraging DL-Proline-[4-13C] for metabolic flux analysis enables researchers to delve into the intricate pathways of metabolite flow within cells. By tracking the incorporation of the [4-13C] label into diverse metabolites, scientists can quantify fluxes and gauge metabolic activity. This data is indispensable for unraveling the complexities of cellular metabolism and fine-tuning industrial bioprocesses.

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, DL-Proline-[4-13C] stands as a labeled standard for exploring protein folding dynamics and interactions. The presence of the 13C label grants a sensitivity and resolution advantage, facilitating detailed structural elucidation. Researchers harness DL-Proline-[4-13C] to scrutinize specific proline sites within proteins, enhancing comprehension of protein structure-function correlations.

Biomolecular Research: Within biomolecular simulations and experimental investigations, DL-Proline-[4-13C] serves as a valuable tool to uncover proline's contributions to protein dynamics. By integrating this labeled amino acid into peptide sequences, scientists can track conformational changes and proline-specific interactions, shedding light on the influence of proline residues on protein stability and functionality.

Cancer Research: In the domain of cancer research, DL-Proline-[4-13C] plays a pivotal role in exploring the altered proline metabolism within tumor cells. The labeled compound empowers researchers to dissect how cancer cells manipulate proline metabolism distinctively from normal cells. Such insights aid in pinpointing potential metabolic vulnerabilities that could be exploited for therapeutic interventions.