Name: Dodecylphosphorylcholine-[d38]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-009256

CAS: 130890-78-7

Molecular Formula: C17D38NO4P

Molecular Weight: 389.69

Chemical Structure

Description	Labelled Dodecylphosphorylcholine. Dodecylphosphocholine is a detergent used in NMR for membrane protein structure determination.
Synonyms	N-Dodecylphosphocholine-D38; 2-[[(dodecyl-d25-oxy)hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-ethan-1,1,2,2-d4-aminium, inner salt
IUPAC Name	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-pentacosadeuteriododecyl [1,1,2,2-tetradeuterio-2-[tris(trideuteriomethyl)azaniumyl]ethyl] phosphate
Related CAS	29557-51-5 (unlabelled)
Isomeric SMILES	[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])OP(=O)([O-])OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
Canonical SMILES	CCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C
InChI	InChI=1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3/i1D3,2D3,3D3,4D3,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2
InChI Key	QBHFVMDLPTZDOI-DHIOKLJKSA-N
Melting Point	247-249°C (lit.)
Purity	98 atom % D
Appearance	Powder
Shelf Life	1 Year
Storage	Store at -20°C

Dodecylphosphorylcholine-[d38], a deuterated surfactant with diverse scientific and industrial applications, plays a pivotal role in various fields. Here are key applications of Dodecylphosphorylcholine-[d38] presented with high perplexity and burstiness:

Nuclear Magnetic Resonance (NMR) Studies: In the realm of NMR studies, Dodecylphosphorylcholine-[d38] emerges as a crucial detergent, facilitating investigations into the structure and dynamics of membrane proteins. Its deuteration reduces background noise, enhancing NMR signal clarity significantly. This surfactant serves as an indispensable tool for researchers delving into the structural complexities of biomolecules within a membrane-like milieu.

Pharmaceutical Formulation: Within the pharmaceutical landscape, Dodecylphosphorylcholine-[d38] finds utility as a surfactant offering stabilization to liposomal drug formulations. By aiding in the creation of stable phospholipid bilayers, it enhances the encapsulation of therapeutic agents, thereby improving bioavailability and targeted delivery. This surfactant plays a critical role in fostering the development of innovative drug delivery systems, revolutionizing pharmaceutical practices.

Microscopy: Embarking on electron microscopy endeavors, researchers harness Dodecylphosphorylcholine-[d38] to visualize cellular membranes and their associated proteins with clarity. When preparing samples for analysis, this surfactant preserves membrane structures under high-vacuum conditions, ensuring their integrity remains intact. Its contribution to high-resolution imaging facilitates in-depth exploration of cellular ultrastructure, providing valuable insights into cellular organization.

Biophysical Research: In the pursuit of understanding lipid bilayer dynamics, Dodecylphosphorylcholine-[d38] emerges as a fundamental component. Acting as a model membrane element, it aids researchers in evaluating the effects of diverse physical and chemical factors on lipid bilayer stability and fluidity. The insights gained from these studies are crucial for unraveling the dynamics and interactions within biological membranes, shedding light on intricate biophysical phenomena.