About Us Careers Contact Us

Home
Products
Isotope Labeled Active Pharmaceutical Ingredients (APIs)
Dolutegravir-d5

Products

Inquiry List

* Name:
* Phone:
* Service & Products of Interested: [Isotope Labeled Active Pharmaceutical Ingredients (APIs)] Dolutegravir-d5 (BLP-015145)
Project Description:
* Quantity
* Email:
* Organization We recommend you to leave us your work email address so that we can serve you better. Please leave your organization information here if you don't have a work email address.
* Verification Code:

Our Highlights

Optimal Prices
Buying products on this site guarantees the best price
Flexible Batches
Flexible batch size to meet different needs of global customers
Prompt Delivery
Warehouses in multiple cities to ensure timely delivery
Quality Assurance
Strict process parameter control to ensure product quality
One-to-one Customization
One-to-one custom synthesis for special structural needs

Application Area

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Dolutegravir-d5

Name: Dolutegravir-d5
Brand: BOC Sciences
Rating: 5 (1 reviews)

Inquiry

General Information
Catalog: BLP-015145
Molecular Formula: C20H14D5F2N3O5
Molecular Weight: 424.41

Chemical Structure

Description	Dolutegravir-d5 is used as an internal standard for the quantification of dolutegravir by GC- or LC-MS. Dolutegravir is a potent and orally bioavailable HIV integrase strand transfer inhibitor of HIV integrase. It prevents replication of several HIV-1 strains (EC50s = 0.36-2.1 nM) in peripheral blood mononuclear cells (PBMCs).
Synonyms	(4R,12aS)-N-((2,4-difluorophenyl-3,5,6-d3)methyl-d2)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Related CAS	1051375-16-6 (unlabelled)
Canonical SMILES	FC1=C([2H])C(F)=C([2H])C([2H])=C1C([2H])([2H])NC(C2=CN(C[C@@](OCC[C@H]3C)([H])N3C4=O)C4=C(O)C2=O)=O
InChI	InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1/i2D,3D,6D,7D2
InChI Key	RHWKPHLQXYSBKR-DZYLKJILSA-N
Purity	≥99% atom D
Appearance	Solid Powder