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Doravirine-[13C6]

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General Information
Catalog: BLP-001304
Molecular Formula: C11[13C]6H11ClF3N5O3
Molecular Weight: 431.71

Chemical Structure

Description	Labelled Doravirine. Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going.
Related CAS	1338225-97-0 (unlabelled)
Purity	98%; 99% atom 13C