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Dovitinib-[d8]

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General Information
Catalog: BLP-014011
CAS: 1246819-84-0
Molecular Formula: C21H13D8FN6O
Molecular Weight: 400.48

Chemical Structure

Description	Dovitinib-[d8] is the labelled analogue of Dovitinib. Dovitinib is a receptor tyrosine kinase (RTK) inhibitor that exhibits an suppressive effect of tumor growth.
Synonyms	Dovitinib-D8; 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone-d8; 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one-d8; GFKI 258-d8; TKI 258-d8
IUPAC Name	4-amino-5-fluoro-3-[6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4aH-quinolin-2-one
Related CAS	405169-16-6 (unlabelled)
Canonical SMILES	CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5C(=NC4=O)C=CC=C5F)N
InChI	InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11,17H,7-10,23H2,1H3,(H,24,25)/i7D2,8D2,9D2,10D2
InChI Key	VRLGJSYPIOVRLQ-UFBJYANTSA-N
Purity	>95%
Solubility	Soluble in DMSO
Appearance	Crystalline Solid
Storage	Store at -20°C