Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-001686 |
CAS: 1217230-31-3 |
Molecular Formula: C21[13C]4H22N4O4 |
Molecular Weight: 446.44 |
Chemical Structure |
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Description | Eltrombopag-[13C4] is used as an internal standard for the quantification of eltrombopag by GC or LC-MS. Eltrombopag-[13C4] is the labelled analogue of Eltrombopag. Eltrombopag is an orally bioavailable nonpeptide agonist of the thrombopoietin receptor which is used as treatment for thrombocytopenia. |
Synonyms | [13C4]-Eltrombopag; Eltrombopag-13C4; CTK8F9430; (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-(methyl-13C)-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene-3,4,5-13C3)hydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylicacid; SB 497115-13C4 |
IUPAC Name | 3-[3-[[2-(3,4-dimethylphenyl)-5-(1-13C)methyl-3-oxo-(3,4,5-13C3)1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid |
Related CAS | 496775-61-2 (unlabelled) |
Canonical SMILES | OC1=C(N/N=[13C]2[13C](N(C3=CC(C)=C(C)C=C3)N=[13C]\2[13CH3])=O)C=CC=C1C4=CC(C(O)=O)=CC=C4 |
InChI | InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-/i3+1,16+1,22+1,24+1 |
InChI Key | XDXWLKQMMKQXPV-PHYJMDTMSA-N |
Melting Point | > 120 °C (dec.) |
Purity | > 95% by HPLC; > 98% atom 13C |
Solubility | Slightly soluble in DMSO |
Appearance | Orange Solid |
Storage | 2-8 °C under inert atmosphere |
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