Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-006954 |
CAS: 2482467-27-4 |
Molecular Formula: C26[13C]3H44O3 |
Molecular Weight: 443.64 |
Chemical Structure |
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Description | Estradiol undecylate (2,3,4-13C3) is an isotope labelled Estradiol undecylate. Estradiol undecylate isa synthetic estrogen ester which acts as a prodrug of estradiol. |
Synonyms | 17β-Estradiol-2,3,4-13C3 17-undecanoate; 17β-Estradiol Undecanoate-[13C3]; 17β-Estradiol-13C3 Undecanoate |
IUPAC Name | (8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[i]phenanthren-17-yl-2,3,4-13C3 undecanoate |
Related CAS | 3571-53-7 (unlabelled) |
Purity | 95% by CP; 98% atom 13C |
Storage | Store at -20°C |
Estradiol undecylate-[2,3,4-13C3], a labeled derivative of estradiol, finds diverse applications in research and preclinical settings. Here are the key applications:
Pharmacokinetics Studies: Employed in pharmacokinetic studies, Estradiol undecylate-[2,3,4-13C3] serves as a vital tool for tracking and quantifying the metabolism and distribution of estradiol within the body. By utilizing this labeled compound, researchers can meticulously trace the biochemical pathways and ascertain the fate of estradiol in the metabolic milieu. This information plays a pivotal role in fine-tuning hormone replacement therapies and unraveling intricate drug interactions.
Hormone Research: In the realm of hormone research, Estradiol undecylate-[2,3,4-13C3] takes center stage in exploring the effects of estradiol on diverse biological systems. Incorporating the labeled estradiol facilitates precise monitoring of receptor binding, gene transcription, and downstream effects, offering unparalleled insights into the molecular mechanisms of estrogen action and its implications for health and disease pathophysiology.
Endocrinology: Within the domain of endocrinology, Estradiol undecylate-[2,3,4-13C3] emerges as a key player in deciphering the nuances of hormonal regulation and equilibrium within the endocrine system. Researchers leverage this compound to delve into the intricate interactions of estradiol with other hormones and its impacts on physiological processes like reproduction, metabolism, and bone maintenance. This knowledge contributes significantly to advancing our comprehension of hormonal dysregulations and enhancing therapeutic interventions.
Environmental Sciences: Stepping into the realm of environmental sciences, Estradiol undecylate-[2,3,4-13C3] offers valuable insights into the presence and consequences of endocrine-disrupting compounds in ecosystems. By integrating this labeled compound into environmental studies, scientists can effectively monitor the absorption, distribution, and degradation patterns of estradiol-like substances in ecological settings. This holistic approach aids in assessing environmental risks associated with these compounds and formulating informed regulatory measures to safeguard environmental and human health.
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