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Estrone, 3-methyl ether-[13C,d3]

General Information
Catalog: BLP-005357
CAS: 1261254-60-7
Molecular Formula: C18[13C]H21D3O2
Molecular Weight: 288.40
Chemical Structure
Estrone, 3-methyl ether-[13C,d3]
Synonyms Estrone, 3-methyl-[13C,D3] ether
IUPAC Name (8R,9S,13S,14S)-13-methyl-3-(trideuterio(1-13C)methoxy)-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Related CAS 1624-62-0 (unlabelled)
Canonical SMILES CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OC
InChI InChI=1S/C19H24O2/c1-19-10-9-15-14-6-4-13(21-2)11-12(14)3-5-16(15)17(19)7-8-18(19)20/h4,6,11,15-17H,3,5,7-10H2,1-2H3/t15-,16-,17+,19+/m1/s1/i2+1D3
InChI Key BCWWDWHFBMPLFQ-KERBJVJDSA-N
Density 1.1±0.1 g/cm3
Storage Store at -20°C

Estrone, 3-methyl ether-[13C,d3] is a stable isotope-labeled compound with diverse applications in research and analysis. Explore its key applications presented with high perplexity and burstiness:

Metabolic Studies: Delving into estrogen metabolism, Estrone, 3-methyl ether-[13C,d3] emerges as a pivotal tracer, shedding light on biochemical pathways and metabolic kinetics. Researchers leverage this labeled compound as a tool to meticulously monitor and quantify the conversion of estrogens within biological systems. This application not only enriches our understanding of hormone metabolism, but also unveils its far-reaching implications in the realm of health and disease.

Pharmacokinetic Research: Embarking on pharmacokinetic endeavors, Estrone, 3-methyl ether-[13C,d3] assumes a crucial role in evaluating the absorption, distribution, metabolism, and excretion (ADME) profiles of estrogen compounds. By harnessing this labeled compound, scientists embark on a precise assessment of the bioavailability and half-life of potential drug candidates. Such meticulous characterization lays the foundation for optimizing dosing regimens and ensuring the safety and efficacy of pharmaceutical interventions.

Analytical Chemistry: Within the domain of analytical chemistry, Estrone, 3-methyl ether-[13C,d3] emerges as a beacon, serving as an internal standard in mass spectrometry and chromatography techniques. Its utilization facilitates the accurate quantification of estrone-related compounds within intricate biological samples. This application stands as a cornerstone in clinical diagnostics and environmental monitoring, where the meticulous measurement of hormone levels is paramount for informed decision-making.

Endocrinology Research: Unraveling the mysteries of endocrinology, Estrone, 3-methyl ether-[13C,d3] steps into the spotlight, offering a gateway to investigating the roles of estrogens and their metabolites in both physiological nuances and pathological conditions. Researchers harness this labeled compound to navigate the intricate landscape of estrogen receptor interactions and signaling pathways. This exploration yields valuable insights into hormonal regulation, paving the way for potential therapeutic interventions in the realm of hormone-related disorders.

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