| Description |
Everolimus-[d4] is the labelled analogue of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. |
| Synonyms |
Everolimus D4; 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4 |
| IUPAC Name |
(1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R,4R)-3-methoxy-4-(1,1,2,2-tetradeuterio-2-hydroxyethoxy)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone |
| Related CAS |
159351-69-6 (unlabelled)
|
| Canonical SMILES |
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC |
| InChI |
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1/i24D2,25D2 |
| InChI Key |
HKVAMNSJSFKALM-FQJUTLEBSA-N |
| Boiling Point |
998.7±75.0 °C at 760 mmHg |
| Melting Point |
>80°C (dec.) |
| Purity |
95% by HPLC; 95% atom D |
| Density |
1.2±0.1 g/cm3 |
| Solubility |
Soluble in Chloroform, Methanol |
| Appearance |
Off-white to Pale Yellow Solid |
| Storage |
Store at -20°C |
![Everolimus-[d4]](https://resource.bocsci.com/structure/1338452-54-2.gif)
