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Furamidine-[d8]

General Information
Catalog: BLP-005520
CAS: 336786-81-3
Molecular Formula: C18H8D8N4O
Molecular Weight: 312.40
Chemical Structure
Furamidine-[d8]
Description Furamidine-[d8] is a deuterium labelled form of Furamidine. Furamidine dihydrochloride is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4 μM) in the class of antimicrobial and antiparasitic agents. It was shown to inhibit cell proliferation in leukemia cell lines.
Synonyms 4,4'-(2,5-Furandiyl)bisbenzenecarboximidamide; 2,5-Bis(4-amidinophenyl)furan-d8; Furamidine D8
IUPAC Name 4-[5-(4-carbamimidoyl-2,3,5,6-tetradeuteriophenyl)furan-2-yl]-2,3,5,6-tetradeuteriobenzenecarboximidamide
Related CAS 73819-26-8 (unlabelled)
Canonical SMILES C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N
InChI InChI=1S/C18H16N4O/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22/h1-10H,(H3,19,20)(H3,21,22)/i1D,2D,3D,4D,5D,6D,7D,8D
InChI Key ZJHZBDRZEZEDGB-PGRXLJNUSA-N
Boiling Point 482.4±55.0°C at 760 mmHg
Density 1.3±0.1 g/cm3
Storage Store at 2-8°C

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