Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-005520 |
CAS: 336786-81-3 |
Molecular Formula: C18H8D8N4O |
Molecular Weight: 312.40 |
Chemical Structure |
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Description | Furamidine-[d8] is a deuterium labelled form of Furamidine. Furamidine dihydrochloride is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4 μM) in the class of antimicrobial and antiparasitic agents. It was shown to inhibit cell proliferation in leukemia cell lines. |
Synonyms | 4,4'-(2,5-Furandiyl)bisbenzenecarboximidamide; 2,5-Bis(4-amidinophenyl)furan-d8; Furamidine D8 |
IUPAC Name | 4-[5-(4-carbamimidoyl-2,3,5,6-tetradeuteriophenyl)furan-2-yl]-2,3,5,6-tetradeuteriobenzenecarboximidamide |
Related CAS | 73819-26-8 (unlabelled) |
Canonical SMILES | C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N |
InChI | InChI=1S/C18H16N4O/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22/h1-10H,(H3,19,20)(H3,21,22)/i1D,2D,3D,4D,5D,6D,7D,8D |
InChI Key | ZJHZBDRZEZEDGB-PGRXLJNUSA-N |
Boiling Point | 482.4±55.0°C at 760 mmHg |
Density | 1.3±0.1 g/cm3 |
Storage | Store at 2-8°C |
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