Galpα1,3-[U-13C6]Galpβ1,4GlcpNAc

Galpα1,3-[U-13C6]Galpβ1,4GlcpNAc, a labeled carbohydrate molecule, is widely utilized in glycoscience and its related domains. Here are the key applications of Galpα1,3-[U-13C6]Galpβ1,4GlcpNAc:

Glycan Structure Elucidation: Pioneering researchers harness this labeled carbohydrate to delve into the enigmatic realms of complex glycans, unraveling their intricate structures and deciphering their biosynthetic pathways. The incorporation of this compound fuels in-depth NMR and mass spectrometry analyses, offering profound insights into sugar linkages and the myriad molecular conformations that shape these intricate molecules. This in-depth exploration proves invaluable in advancing our understanding of carbohydrate chemistry and shedding light on the intricacies of glycoprotein synthesis.

Metabolic Labeling Studies: Galpα1,3-[U-13C6]Galpβ1,4GlcpNAc emerges as a potent tool in cell culture systems, illuminating the convoluted pathways of glycan synthesis and tracing their metabolic fate with unparalleled precision. By integrating this labeled compound into cellular glycans, researchers embark on an enlightening journey, employing cutting-edge isotope tracing techniques to unravel the complex intricacies of cellular metabolism. This application stands as a cornerstone in unraveling the mysteries of metabolic pathways, paving the way for the identification of potential drug targets in diseases like cancer and beyond.

Diagnostics: The versatile molecule serves as a linchpin in diagnostic assays, enabling the rapid detection of glycan abnormalities that serve as potent indicators of underlying diseases. When deployed as a standard or probe in mass spectrometry, this labeled compound facilitates the meticulous quantification of glycan structures in biological samples, offering a window into the subtle intricacies of disease pathology. This innovative approach proves pivotal in early disease diagnosis and spearheading groundbreaking biomarker discoveries that have the potential to revolutionize healthcare practices.

Glycoproteomics Research: Within the domain of proteomics, Galpα1,3-[U-13C6]Galpβ1,4GlcpNAc emerges as a beacon of hope, allowing researchers to delve into the complex world of glycoproteins and unravel the intricate dance of glycosylation patterns that dictate protein functionality. The distinctive isotopic signature of this labeled compound serves as a powerful ally, enabling the precise identification and characterization of glycoproteins within complex biological mixtures. This fundamental understanding of protein-glycan interactions serves as a cornerstone for deciphering the subtle nuances of protein functionality and unraveling the mysteries that govern biological processes at their core.