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Gilteritinib-[d3]

General Information
Catalog: BLP-015085
CAS: 2377109-67-4
Molecular Formula: C29H41D3N8O3
Molecular Weight: 555.73
Chemical Structure
Gilteritinib-[d3]
Description Gilteritinib-[d3] is an isotope labelled Gilteritinib, a potent FLT3/AXL inhibitor used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations.
Synonyms 6-Ethyl-3-((3-methoxy-4-(4-(4-(methyl-d3)piperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; Gilteritinib d3; 6-Ethyl-3-[[3-methoxy-4-[4-[4-(methyl-d3)-1-piperazinyl]-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide; ASP 2215-d3; Gilteritinib-d3
IUPAC Name 6-ethyl-3-[3-methoxy-4-[4-[4-(trideuteriomethyl)piperazin-1-yl]piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
Related CAS 1254053-43-4 (unlabelled)
Canonical SMILES [2H]C([2H])([2H])N1CCN(CC1)C2CCN(CC2)C3=C(C=C(C=C3)NC4=NC(=C(N=C4C(=O)N)CC)NC5CCOCC5)OC
InChI InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34)/i2D3
InChI Key GYQYAJJFPNQOOW-BMSJAHLVSA-N
Purity >95%
Storage Store at 2-8 °C

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