Glycan-N48-13C-GAL6,6',6''-[galactose-13C18]

Glycan-N48-13C-GAL6,6',6''-[galactose-13C18] is a sophisticated labeled glycoconjugate utilized for research purposes in the exploration of carbohydrate chemistry and glycoscience. Here are key applications of Glycan-N48-13C-GAL6,6',6''-[galactose-13C18] presented with elevated perplexity and burstiness:

Metabolic Labeling Studies: Employing this distinct glycan in metabolic labeling experiments allows researchers to trace and dissect carbohydrate metabolic pathways within cellular environments. By integrating the labeled galactose into glycan structures, scientists can meticulously track the synthesis and modification of glycoproteins and glycolipids. This knowledge plays a pivotal role in comprehending cellular metabolism and pinpointing deviations in disease conditions.

Glycomics Research: Glycan-N48-13C-GAL6,6',6''-[galactose-13C18] serves as an indispensable tool in the realm of glycomics, aiding in unraveling the intricate structures and functions of glycans within biological systems. The isotopic labeling facilitates the precise quantification of glycans using mass spectrometry, offering deep insights into glycan compositions and their alterations during developmental processes or disease states. This contributes significantly to the discovery of biomarkers and the exploration of glycan-mediated biological phenomena.

Proteomics Studies: In the domain of proteomics, the incorporation of Glycan-N48-13C-GAL6,6',6''-[galactose-13C18] into glycoproteins enables detailed scrutiny of protein glycosylation patterns. Researchers can leverage this labeled glycan to pinpoint and measure glycosylated peptides in complex biological samples. Understanding glycosylation is imperative for delving into protein functionality, stability, and intricate interactions, shedding light on crucial aspects of cellular processes.

Structural Biology: Glycan-N48-13C-GAL6,6',6''-[galactose-13C18] finds application in structural biology for probing the three-dimensional arrangement of glycoproteins and carbohydrate chains. Through the examination of labeled glycans, researchers can deduce the orientation and interplay of sugars within macromolecular structures using advanced techniques like NMR spectroscopy. This comprehension aids in unraveling the structural underpinnings of glycan functionality and its interactions with proteins, enriching our knowledge of molecular intricacies.