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Henatinib-[13C6]

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General Information
Catalog: BLP-001326
Molecular Formula: C19[13C]6H29FN4O4
Molecular Weight: 474.48

Chemical Structure

Description	A labelled version of Henatinib. Henatinib maleate is the maleate salt form of henatinib, an orally bioavalable, multitargeted tyrosine kinase inhibitor with potential antitumor and antiangiogenic activities. Henatinib inhibits vascular endothelial growth factor receptor type 2 (VEGFR2), a tyrosine kinase receptor upregulated in many tumor cells that plays a key role in angiogenesis. This may result in an inhibition of angiogenesis and eventually tumor cell proliferation. Henatinib, structurally similar to sunitinib, also inhibits, though to a lesser extent, mast/stem cell growth factor receptor (c-Kit) and, platelet-derived growth factor receptor (PDGFR) alpha and beta.
Related CAS	1239269-51-2 (unlabelled)
Purity	98%; 99% atom 13C