Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-011889 |
CAS: 74495-71-9 |
Molecular Formula: C9H7D3O4 |
Molecular Weight: 185.19 |
Chemical Structure |
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Catalog Number | Size | Price | Stock | Quantity |
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BLP-011889 | 10 mg | $1199 | In stock |
Description | Homovanillic Acid-[d3] is an isotopically-labeled version of Homovanillic Acid (HVA). This important dopamine metabolite is predominantly found in human urine and is a valuable biochemical research tool for investigating the mechanisms underlying neuropsychiatric and neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and schizophrenia. Its use in these studies is useful, given the marked alterations in dopamine metabolism and function that are observed in these conditions. |
Synonyms | Homovanillic Acid D3 |
IUPAC Name | 2-[4-hydroxy-3-(trideuteriomethoxy)phenyl]acetic acid |
Related CAS | 306-08-1 (unlabelled) |
Isomeric SMILES | [2H]C([2H])([2H])OC1=C(C=CC(=C1)CC(=O)O)O |
Canonical SMILES | COC1=C(C=CC(=C1)CC(=O)O)O |
InChI | InChI=1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)/i1D3 |
InChI Key | QRMZSPFSDQBLIX-FIBGUPNXSA-N |
Melting Point | 135-137°C |
Purity | 95% atom D |
Solubility | Soluble in DMSO, Methanol |
Appearance | White to Off-white Solid |
Application | A neuroendocrine tumor marker. A Labelled metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase. |
Storage | Store at -20°C |
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