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Homovanillic Acid-[d3]

General Information
Catalog: BLP-011889
CAS: 74495-71-9
Molecular Formula: C9H7D3O4
Molecular Weight: 185.19
Chemical Structure
Homovanillic Acid-[d3]
Catalog Number Size Price Stock Quantity
BLP-011889 10 mg $1199 In stock
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Description Homovanillic Acid-[d3] is an isotopically-labeled version of Homovanillic Acid (HVA). This important dopamine metabolite is predominantly found in human urine and is a valuable biochemical research tool for investigating the mechanisms underlying neuropsychiatric and neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and schizophrenia. Its use in these studies is useful, given the marked alterations in dopamine metabolism and function that are observed in these conditions.
Synonyms Homovanillic Acid D3
IUPAC Name 2-[4-hydroxy-3-(trideuteriomethoxy)phenyl]acetic acid
Related CAS 306-08-1 (unlabelled)
Isomeric SMILES [2H]C([2H])([2H])OC1=C(C=CC(=C1)CC(=O)O)O
Canonical SMILES COC1=C(C=CC(=C1)CC(=O)O)O
InChI InChI=1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)/i1D3
InChI Key QRMZSPFSDQBLIX-FIBGUPNXSA-N
Melting Point 135-137°C
Purity 95% atom D
Solubility Soluble in DMSO, Methanol
Appearance White to Off-white Solid
Application A neuroendocrine tumor marker. A Labelled metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase.
Storage Store at -20°C

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