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iCRT-14-[d5]

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General Information
Catalog: BLP-019868
CAS: 1795144-12-5
Molecular Formula: C21H12D5N3O2S
Molecular Weight: 380.47

Chemical Structure

Description	A labelled potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between β-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
Synonyms	5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-(phenyl-d5)-2,4-thiazolidinedione; iCRT 14-d5; iCRT14-d5;