| Description |
Ivabradine-[d3] Hydrochloride is the labelled salt of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. |
| Synonyms |
Ivabradine-D3 Hydrochloride; Ivabradin D3 HCl; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3 Hydrochloride; Procoralan-d3 Hydrochloride |
| IUPAC Name |
3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-(trideuteriomethyl)amino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride |
| Related CAS |
148849-67-6 (unlabelled) 155974-00-8 (unlabelled free base)
|
| Isomeric SMILES |
[2H]C([2H])([2H])N(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.Cl |
| Canonical SMILES |
CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CC3CC4=CC(=C(C=C34)OC)OC.Cl |
| InChI |
InChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1/i1D3 |
| InChI Key |
HLUKNZUABFFNQS-AFMQDYKRSA-N |
| Melting Point |
99-102°C |
| Purity |
>95% |
| Solubility |
Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance |
Tan Solid |
| Application |
The hydrochloride salt form of isotope labelled Ivabradine |
| Shelf Life |
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
| Storage |
Store at -20°C under inert atmosphere |
![Ivabradine-[d3] Hydrochloride](https://resource.bocsci.com/structure/1217809-61-4.gif)
