L-(+)-2-Phenylglycine-[d5]

L-(+)-2-Phenylglycine-[d5], a labeled amino acid utilized in diverse scientific research applications, is a key player in the realm of molecular exploration. Here are the key applications:

Metabolic Flux Analysis: The integration of L-(+)-2-Phenylglycine-[d5] in metabolic flux analysis studies allows researchers to delve into intricate metabolic pathways and assess alterations in metabolic networks. By infusing this labeled compound into metabolic pathways, scientists can track the destiny and turnover of metabolic intermediates, shedding light on the depths of cellular metabolism and pinpointing crucial regulatory nodes.

Pharmaceutical Research: At the forefront of pharmaceutical research, L-(+)-2-Phenylglycine-[d5] serves as an isotopic standard for the precise quantification and analysis of drug metabolites. Its stable isotope labeling facilitates accurate mass spectrometric analysis, ensuring the precise measurement of drug concentration and metabolism. This meticulous approach is pivotal for pharmacokinetic and pharmacodynamic studies, guiding drug development strategies and dosing regimens with precision.

Structural Biology: Delving into the intricate world of proteins and enzymes, L-(+)-2-Phenylglycine-[d5] offers insights into the complex structure-function relationships governing these biomolecules. When integrated into proteins, this labeled amino acid unravels mysteries surrounding protein folding, binding interactions, and conformational shifts through cutting-edge techniques like NMR and mass spectrometry. This knowledge fuels the rational design of drugs and therapeutic interventions, unlocking new avenues for biomedical advancements.

Environmental Studies: In the domain of environmental sciences, L-(+)-2-Phenylglycine-[d5] plays a crucial role in tracer studies aimed at unraveling the fate and transportation patterns of organic contaminants in the environment. By meticulously tracking this labeled compound in environmental samples, researchers can decipher biodegradation pathways, gauge microbial activity, and evaluate contaminant persistence. This invaluable information forms the bedrock for devising effective remediation strategies and assessing the environmental impact of contaminants.