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L-ascorbic acid-[6,6'-d2]

General Information
Catalog: BLP-007046
Molecular Formula: C6H6D2O6
Molecular Weight: 178.14
Chemical Structure
L-ascorbic acid-[6,6'-d2]
Description Labelled Ascorbic Acid. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs.
Synonyms L-[6,6'-2H2]ascorbic acid; [6,6'-2H2]vitamin C; L-ascorbic acid-6,6-d2; L-[6,6'-D2]ascorbic acid
IUPAC Name 5-(1,2-dihydroxyethyl-2,2-d2)-3,4-dihydroxyfuran-2(5H)-one
Related CAS 50-81-7 (unlabelled)
Appearance White to Off-White Solid
Storage Store at 2-8°C

L-ascorbic acid-[6,6'-d2], a labeled form of vitamin C utilized in diverse scientific research and applications, offers insights into vitamin C metabolism and uptake in biological systems. Here are the key applications:

Nutritional Biochemistry: Delving into the intricacies of vitamin C, L-ascorbic acid-[6,6'-d2] serves as a critical tool in unraveling the pathways of vitamin C processing within the body. Through the use of this labeled compound, researchers can precisely track and quantify the metabolic fate of vitamin C, shedding light on nutrient utilization and aiding in the development of advanced nutritional supplements.

Pharmaceutical Research: Pushing the boundaries of clinical inquiry, this labeled compound plays a pivotal role in exploring the kinetics and distribution of vitamin C in varied tissues and fluids. By meticulously monitoring L-ascorbic acid-[6,6'-d2], scientists can gather valuable data on absorption rates, half-life, and excretion patterns, informing the design of targeted vitamin C therapies and optimal dosage regimens.

Antioxidant Mechanism Studies: At the forefront of antioxidative research, L-ascorbic acid-[6,6'-d2] enables a profound exploration of vitamin C's antioxidant properties at a molecular level. Leveraging the labeled version, researchers can intricately trace the interactions between vitamin C and free radicals, gaining a comprehensive understanding of the mechanisms underlying oxidative stress. This knowledge drives the development of innovative strategies to combat diseases associated with oxidative damage.

Isotope Dilution Analysis: Serving as a cornerstone in isotope dilution methodologies, L-ascorbic acid-[6,6'-d2] facilitates precise measurements of vitamin C levels across various samples, including biological tissues, food products, and dietary supplements. This technique offers unparalleled accuracy and consistency in quantifying vitamin C content, supporting nutritional labeling, quality assurance, and adherence to dietary guidelines.

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